On June 4, Akeso (09926.HK) fell 3.16% in regular trading, trading at HKD 99.3/share with trading volume of HKD 434 million, breaking below the psychologically significant HKD 100 level.
The decline represents a continuation of profit-taking following the realization of a major catalyst at the ASCO annual meeting. On June 1, the company presented positive interim OS results from its Phase III HARMONi-6 study of ivonescimab plus chemotherapy in first-line squamous NSCLC, achieving an HR of 0.66 (P=0.0017) with a 34% reduction in death risk — the first global Phase III study to demonstrate both OS and PFS superiority over PD-1 plus chemotherapy in lung cancer. Despite the landmark data, event-driven funds have been systematically exiting positions since the data release, with the stock declining over 14% cumulatively across three sessions. Reports that the US may restrict investment in Chinese biotech further weighed on sector sentiment. Within the Biotechnology sector, BeiGene rose 2.84%, while Innovent fell 0.78%, 3SBio fell 2.02%, RemeGen fell 0.48%, and DualityBio fell 4.35%.
(The above content is based on publicly available market information, generated by a program or algorithm, and is intended solely as a stock movement alert. It does not constitute investment advice or a basis for trading decisions.)
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