BillionToOne, Inc. (NASDAQ: BLLN) experienced a significant after-hours surge of 6.40% on Wednesday, following the release of its fourth quarter and full year 2025 financial results.
The molecular diagnostics company reported quarterly earnings of $0.11 per share, which substantially beat the analyst consensus estimate of $0.03. This represents a dramatic swing from a loss of $1.13 per share in the same period last year. Quarterly sales reached $96.053 million, surpassing estimates of $87.161 million and marking a 113% year-over-year increase.
Furthermore, the company raised its full-year 2026 revenue guidance to a range of $430 million to $445 million, up from its previous outlook of $415 million to $430 million and well above the FactSet estimate of $405.1 million. BillionToOne also stated it expects positive GAAP operating income for the full year 2026, driven by strong growth in both its prenatal and oncology clinical testing segments.
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