Jiangsu Aidea Pharmaceutical Group Co., Ltd. (688488.SH) announced that its self-developed Class 1 new drug, ACC017 tablets, for the treatment of HIV, has commenced a multicenter, randomized, double-blind, double-dummy, dolutegravir sodium tablet-controlled Phase III clinical trial. The study aims to evaluate the efficacy and safety of ACC017 in treatment-naive adults infected with human immunodeficiency virus type 1 (HIV-1). The first patient was successfully enrolled on November 7, 2025.
ACC017 is a novel chemical-structured HIV integrase strand transfer inhibitor (INSTI) independently developed by the company. As a Class 1 new chemical entity, it effectively blocks the integration of the HIV genome into host DNA by inhibiting HIV integrase activity. The drug is intended for clinical use in treating HIV infections.
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