Stock Track | ImmuneOnco Soars on Global Development Plans for Cancer Bispecific Antibody

Stock Track09-16

Shares of ImmuneOnco Biopharmaceuticals Shanghai Inc. surged by nearly 47% on Monday after the company and its partner Instil Bio announced a global registrational strategy for their bispecific antibody SYN-2510/IMM2510, targeting non-small cell lung cancer (NSCLC) and triple-negative breast cancer (TNBC).

The collaboration plans to initiate a Phase 1b/2 trial in late 2024 in China, evaluating SYN-2510/IMM2510 in combination with chemotherapy as a first-line treatment for NSCLC. Additionally, a similar Phase 1b/2 trial in first-line TNBC is anticipated in early 2025 in China.

Furthermore, Instil Bio plans to submit an Investigational New Drug (IND) application for SYN-2510 in the US by late 2024, with the aim of initiating a Phase 2 trial investigating the bispecific antibody as a monotherapy in second-line NSCLC patients.

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