Significant gains were observed for SKB BIO-B (06990) and HBM HOLDINGS-B (02142) during afternoon trading. At the time of writing, SKB BIO-B had risen by 7.34% to HK$426.8, while HBM HOLDINGS-B increased by 4.65% to HK$11.7. The movement follows an announcement on March 23 that the initial human Phase I clinical trial results for HBM9378 have been published online in the peer-reviewed journal Drug Design, Development and Therapy. The favorable safety profile and extended half-life observed in the study support further evaluation of the therapy for severe immune diseases. Public information indicates that HBM9378 was jointly developed by HBM HOLDINGS-B and SKB BIO-B, with both companies sharing global rights. In January 2025, HBM HOLDINGS-B and SKB BIO-B entered into a strategic collaboration with Windward Bio, granting the latter exclusive rights to research, develop, manufacture, and commercialize the antibody globally, excluding Greater China and certain Southeast and West Asian countries.
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