HENLIUS (02696) saw its shares rise more than 5%. At the time of writing, the stock was up 5.02%, trading at HK$68, with a turnover of HK$19.48 million. The increase follows an announcement on March 5 that the company’s self-developed HLX97, a small molecule inhibitor targeting KAT6A/B, has received Investigational New Drug (IND) approval from the National Medical Products Administration (NMPA) for a Phase 1 clinical trial in patients with advanced or metastatic solid tumors. HLX97 is designed to treat advanced or metastatic solid tumors by inhibiting the activity of lysine acetyltransferases KAT6A and KAT6B. Non-clinical studies have demonstrated that HLX97 exhibits promising anti-tumor efficacy and a favorable safety profile. As of the announcement date, no KAT6A/B small molecule inhibitors have been approved for marketing anywhere in the world.
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