Shenzhen New Industries Biomedical Engineering Co.,Ltd. (300832.SZ) announced that the company has received a Medical Device Registration Certificate issued by the Guangdong Provincial Medical Products Administration for one of its products: the Glutamate Dehydrogenase Assay Kit (α-ketoglutarate substrate method). Glutamate dehydrogenase (GLDH) is an active enzyme widely distributed in the cells of liver, cardiac muscle, and kidney tissues, primarily located within the mitochondrial matrix and inner membrane of these organ tissues. It is a zinc-containing mitochondrial enzyme, with the highest activity found in liver tissue. GLDH plays a crucial role in the catabolism and anabolism of amino acids within the liver, specifically by catalyzing the dehydrogenation and deamination of glutamate to ultimately produce α-ketoglutarate. This reaction is a key step in the deamination and transdeamination process for most amino acids in the body and serves as a central link connecting amino acid metabolism with the tricarboxylic acid cycle.
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