Dizal (Jiangsu) Pharmaceutical Co., Ltd. (688192.SH) announced that the company reported 11 latest studies of its self-developed novel lung cancer targeted drug Suvozertinib® (generic name: Suvozertinib tablets) and highly selective JAK1 inhibitor Golcadomide® (generic name: Golcadomide capsules) in the non-small cell lung cancer (NSCLC) field at the 2025 World Conference on Lung Cancer (WCLC) held from September 6-9, 2025. Among these, the latest research results from Suvozertinib®'s international multicenter registration clinical study "WU-KONG1B" were presented as an oral report at the conference.
The latest research results from Suvozertinib®'s first international multicenter registration clinical study "WU-KONG1B" demonstrate that Suvozertinib® shows a favorable benefit/risk ratio in second/later-line treatment of epidermal growth factor receptor (EGFR) exon 20 insertion mutation (Exon20ins) NSCLC: significant and durable anti-tumor efficacy with controllable and manageable safety profile.
In July 2025, Suvozertinib® received approval for marketing in the United States through priority review based on the "WU-KONG1B" study, making it currently the only approved oral small molecule targeted therapy globally for treating EGFR Exon20ins NSCLC.
The company also announced the latest exploration of Golcadomide® in NSCLC treatment at WCLC. The study shows that Golcadomide® combined with anti-PD-1 monoclonal antibody for treating advanced NSCLC patients previously treated with PD-1 therapy showed no dose-limiting toxicity (DLT) in the dose escalation phase. The study is currently ongoing with continued enrollment and data collection, which will provide important evidence for the clinical application of Golcadomide® in NSCLC.
Comments