Capricor Therapeutics (CAPR) saw its shares drop 8.11% in pre-market trading on Thursday, continuing a downward trend after a massive intraday surge the previous day. The stock had skyrocketed by up to 399% during Wednesday's session following the announcement of positive Phase 3 trial results for its Duchenne muscular dystrophy (DMD) treatment, Deramiocel.
The pre-market decline is attributed to profit-taking by investors who capitalized on the stock's substantial gains. The HOPE-3 study for Deramiocel met both primary and secondary endpoints, demonstrating significant skeletal and cardiac benefits for patients, which had initially fueled the rally.
Nippon Shinyaku, which plans to market CAP-1002 in the U.S. if approved, also announced the positive results, further validating the treatment's potential. The stock's volatility highlights the market's reaction to breakthrough clinical results and subsequent profit-taking.
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