Movement Alert|Alnylam Pharmaceuticals Falls 5.03% in Regular Trading, Amvuttra Faces 340B Reimbursement Policy Uncertainty

Market Focus11-02 23:29

On November 2, Alnylam Pharmaceuticals fell 5.03% in Regular Trading, trading at $156.845 per share, with turnover of $159 million.

The move followed continued market digestion of near-term risk tied to potential changes in the 340B reimbursement framework for Amvuttra, a development that analysts said could weigh on hospital-channel utilization starting in 2027.

Recent company updates added to the pressure. Alnylam reported third-quarter revenue of $1.46 billion, above the $1.43 billion consensus, and adjusted EPS of $16.26, while maintaining total net product revenue guidance at $4.70 billion to $5.10 billion. However, analysts noted TTR revenue is now expected toward the low end of guidance, Amvuttra sales were roughly in line, and part of the quarter benefited from favorable inventory dynamics and a one-time gross-to-net adjustment. Some analysts still argued the selloff appeared overdone given continued execution potential and a large untreated patient population.

(The above content is based on publicly available market information, generated by a program or algorithm, and is intended solely as a stock movement alert. It does not constitute investment advice or a basis for trading decisions.)

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