Stock Track | Beam Therapeutics Soars on Promising Sickle Cell Therapy Data

Stock Track11-06

Beam Therapeutics, Inc. (BEAM) stock surged 8.23% in pre-market trading on November 6, 2024, after the company reported encouraging initial clinical data from its Phase 1/2 BEACON trial evaluating BEAM-101 for the treatment of sickle cell disease.

The data showed that BEAM-101, an investigational cell therapy administered via hematopoietic stem cell transplantation, achieved robust fetal hemoglobin (HbF) induction of over 60% and reduced sickle hemoglobin (HbS) to less than 40% in patients. This hemoglobin profile mimics that of individuals with sickle cell trait, who are typically asymptomatic.

Furthermore, BEAM-101 demonstrated a favorable safety profile consistent with myeloablative conditioning and stem cell transplant. Notably, the therapy facilitated rapid neutrophil engraftment, with all patients engrafting in under 20 days, potentially leading to shorter hospital stays.

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