Zenas BioPharma Inc. (ZBIO) shares surged 6.45% in pre-market trading on Tuesday, driven by positive clinical development news for its lead autoimmune disease therapy.
The company announced that detailed results from its pivotal Phase 3 INDIGO trial for obexelimab in Immunoglobulin G4-Related Disease (IgG4-RD) will be presented at an upcoming medical congress. The trial successfully met its primary endpoint, showing a highly significant 56% reduction in the risk of disease flare compared to placebo over 52 weeks.
Investor sentiment was bolstered by the data, which also indicated that obexelimab met all key secondary efficacy endpoints and demonstrated a favorable safety profile with no new safety signals observed. The announcement provides a significant positive catalyst for the company's late-stage pipeline.
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