Movement Alert|AKESO Falls 3.04% in Regular Trading, Profit-Taking Follows WCLC Data Catalyst Digestion

Market Focus09-16

On September 16, AKESO fell 3.04% in regular trading, trading at HK$92.1/share, with turnover of HK$87.24 million. The decline reflects profit-taking after the company's positive HARMONi-2 overall survival data, presented at the World Conference on Lung Cancer, had already driven the stock up over 5% on September 14.

The WCLC presentation revealed that ivonescimab achieved a median OS of 30.8 months versus 22.6 months for pembrolizumab, with a hazard ratio of 0.73 and a median follow-up of 36 months. While multiple investment banks — including Jefferies (target HK$226), Citi (target HK$171), and JPMorgan — maintained bullish ratings following the data, short selling accounted for 33.18% of turnover on September 15, signaling the positive catalyst had been fully absorbed. Additionally, the company's interim results disclosed in late August showed revenue of RMB 1.806 billion, up 28%, with gross profit of RMB 1.34 billion — both falling short of certain institutional expectations — adding further pressure on near-term sentiment.

(The above content is based on publicly available market information, generated by a program or algorithm, and is intended solely as a stock movement alert. It does not constitute investment advice or a basis for trading decisions.)

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