Metis TechBio partners with Hengrui Pharmaceuticals to deploy AiTEM AI formulation platform

Bulletin Express08-03 12:25

Metis TechBio announced that its proprietary AiTEM artificial-intelligence formulation innovation platform will be locally installed at Jiangsu Hengrui Pharmaceuticals. The cooperation aims to accelerate Hengrui’s drug-formulation workflow and represents the further external commercialisation of AiTEM, which is powered by Metis TechBio’s NanoForge AI-driven nano-delivery infrastructure.

NanoForge integrates an AI-for-nano lipid de novo generation algorithm, a foundational lipid language model and a high-throughput wet-and-dry experimental closed-loop system. As of May 2026, the platform had accumulated more than 10 million lipid structures and 100,000 experimental datapoints, supporting over 10 industry-first or best-in-class R&D programmes and enabling targeted delivery to eight key human organs and tissues.

AiTEM applies the NanoForge dataset to optimise small-molecule formulations by predicting drug–excipient interactions via quantum-chemistry and molecular-dynamics simulations. In the development of MTS-004—the first AI-enabled formulation new drug in China to complete Phase III trials—AiTEM reduced the preclinical formulation-optimisation cycle from the industry norm of one to two years to three months, completing the full discovery-to-Phase III process in 38 months.

Metis TechBio, founded in 2020 by Dr. Hongming Chen, Dr. Tsai-Ta Lai and Dr. Wenshou Wang, debuted on the Hong Kong Stock Exchange on 13 May 2026 as the world’s first listed AI drug-delivery company. Building on NanoForge, the firm offers four core solutions—AiLNP, AiRNA, AiProtein and AiTEM—designed to advance therapeutics across oncology, metabolic, autoimmune and neurodegenerative disease areas.

Shareholders and potential investors are advised to exercise caution, as the announcement contains forward-looking statements subject to uncertainties. The information is based solely on disclosures made by Metis TechBio on 3 August 2026.

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