Movement Alert|Hansoh Pharma Rises 3.51% in Regular Trading, Core ADC Drug HS-20093 Achieves OS Primary Endpoint in Phase III SCLC Trial

Market Focus07-13

On July 13, Hansoh Pharma rose 3.51% in regular trading, trading at HKD 32.78/share, with turnover of HKD 78.47 million.

On the news front, the company announced on July 10 that its self-developed B7-H3 targeted antibody-drug conjugate (ADC) HS-20093 achieved the primary endpoint of overall survival (OS) in a pivotal Phase III clinical trial for small cell lung cancer (SCLC) patients who progressed or relapsed after platinum-containing regimens. Compared to topotecan, the drug demonstrated statistically significant and clinically meaningful improvement in OS, with the secondary endpoint of progression-free survival also showing consistent benefit.

This study represents the first global Phase III trial to confirm significant OS benefit from a B7-H3 ADC in small cell lung cancer. The company stated it will expedite communication with regulatory authorities and advance the new drug application in China. Notably, HS-20093 had previously been granted Breakthrough Therapy Designation by China's NMPA for esophageal squamous cell carcinoma and castration-resistant prostate cancer, underscoring its broad oncology potential.

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