IMMUNEONCO-B (01541) rose more than 9% in afternoon trading, reaching a 7.98% gain at press time to HK$7.31, with a turnover of HK$10.70 million. The company announced during the midday break that its Phase III clinical trial plan for IMM0306 combined with lenalidomide in treating relapsed/refractory follicular lymphoma has been approved by the Center for Drug Evaluation (CDE). This marks an acceleration in the development of innovative therapies for relapsed/refractory follicular lymphoma.
IMM0306 is the world's first CD47 and CD20 dual-targeting bispecific molecule to enter clinical trials. It blocks the "don't eat me" signal, activates macrophages and NK cells, and preferentially binds to CD20 over CD47, effectively eliminating malignant B cells while minimizing toxicity to enhance therapeutic outcomes. The company holds global intellectual property and commercialization rights for IMM0306.
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