INSILICO (03696) released a profit warning for the year ended December 31, 2025, indicating revenue between USD55.80 million and USD56.30 million, significantly lower than the USD85.80 million recorded in 2024. The decline in pipeline development revenue from upfront payments—USD15.00 million to USD15.30 million in 2025 compared to USD58.00 million in 2024—has been identified as a key factor.
A loss attributable to owners in the range of USD352.10 million to USD355.80 million is projected, compared to USD17.10 million for 2024. The increase is primarily linked to a USD296.70 million loss from changes in the fair value of redeemable convertible preferred shares and the aforementioned revenue decline of approximately USD29.50 million to USD30.00 million.
The company also expects an adjusted loss (non-IFRS measures)—which excludes fair value changes of financial liabilities, share-based compensation expenses, and listing expenses—of USD43.60 million to USD47.30 million, increasing from USD22.70 million in 2024. INSILICO notes that the decrease in research and development expenses partially offsets the effects of the revenue shortfall.
The final annual results for 2025 will be published later, and interested parties are advised to review the upcoming announcement in March 2026 for further details.
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