CARSgen Therapeutics Holdings Limited (CARsgen-B, 02171) disclosed that two investigator-initiated trials (IITs) have been selected for poster presentation at the 2026 Annual Congress of the European Hematology Association (EHA).
The accepted abstracts cover: 1. CT0596 – an allogeneic BCMA-targeted CAR-T therapy for refractory/relapsed multiple myeloma (R/R MM) or plasma cell leukemia (PCL). Preliminary IIT results show favorable tolerability and encouraging efficacy signals. Phase Ib trials in R/R MM and primary PCL are planned for 2026. 2. CT1190B – an allogeneic CD19/CD20-targeted CAR-T therapy under evaluation for refractory/relapsed B-cell non-Hodgkin lymphoma (R/R B-NHL). Additional IITs are assessing the candidate in moderate-to-severe refractory systemic lupus erythematosus and refractory/progressive systemic sclerosis. A Phase Ib study in R/R B-NHL is also scheduled for 2026.
Both candidates are developed on CARsgen’s proprietary THANK-u Plus™ platform, which is designed to enhance safety, efficacy, and manufacturing efficiency across hematologic malignancies, solid tumors, and autoimmune diseases.
Abstracts detailing clinical data will be released by EHA on 12 May 2026 at 15:30 CEST, with further information to be provided on the company’s website.
CARsgen emphasizes that successful development and commercialization of CT0596 and CT1190B remain subject to clinical progress and regulatory outcomes, and advises shareholders to exercise caution when dealing in its shares.
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