Movement Alert|GlaxoSmithKline PLC Rises 4.07% in Regular Trading, Lung Cancer Drug Jideytro Achieves 94% Response Rate in First-Line Trial

Market Focus09-14 21:38

On September 14, GlaxoSmithKline PLC rose 4.07% in regular trading, trading at $49.97/share, with turnover of $24.3989 million.

On the news front, the company disclosed clinical trial data for its lung cancer drug zidesamtinib (branded as Jideytro) in first-line treatment of advanced ROS1-positive non-small cell lung cancer, reporting a 94% objective response rate among patients who had not received prior targeted therapy. Notably, all participants with metastatic brain tumors responded to treatment, with 70% achieving complete tumor clearance. Treatment-related adverse events led to dose reductions in only 11% of patients and discontinuations in just 1%. The company plans to submit an application to the FDA this year to expand the drug's approval for first-line use. Jideytro is GSK's first commercialized lung cancer drug, having previously received FDA approval for previously treated ROS1-positive lung cancer.

Additionally, GSK licensor Hansoh Pharmaceutical reported that its ADC drug Ris-Rez met the primary endpoint in a Phase III trial for relapsed small cell lung cancer, further boosting market confidence in GSK's oncology pipeline.

(The above content is based on publicly available market information, generated by a program or algorithm, and is intended solely as a stock movement alert. It does not constitute investment advice or a basis for trading decisions.)

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