CSPC Innovation's Subsidiary Initiates Phase III Clinical Trial for SYS6010

Stock News06-26

CSPC Innovation Pharmaceutical Co.,Ltd. (ASX: 300765) has announced that its controlling subsidiary, Jushi Biopharmaceutical Co., Ltd., recently commenced a Phase III clinical trial for SYS6010.

The trial is a randomized, open-label, multicenter study evaluating SYS6010 in combination with Enlangsubaizumab as a first-line treatment for driver gene-negative, PD-L1 positive locally advanced or metastatic non-small cell lung cancer (NSCLC).

SYS6010 is an antibody-drug conjugate (ADC) targeting the epidermal growth factor receptor (EGFR), developed by Jushi Biopharmaceutical.

The drug is composed of a humanized anti-EGFR monoclonal antibody conjugated to a topoisomerase I inhibitor payload via a cleavable linker.

It works by specifically binding to EGFR receptors on the surface of tumor cells, internalizing, and then releasing its cytotoxic payload inside the cell to exert an anti-tumor effect.

Enlangsubaizumab Injection is a humanized IgG4 variant monoclonal antibody that targets the human programmed cell death protein-1 (PD-1) and is used to treat malignant tumors in various human organs and tissues.

Disclaimer: Investing carries risk. This is not financial advice. The above content should not be regarded as an offer, recommendation, or solicitation on acquiring or disposing of any financial products, any associated discussions, comments, or posts by author or other users should not be considered as such either. It is solely for general information purpose only, which does not consider your own investment objectives, financial situations or needs. TTM assumes no responsibility or warranty for the accuracy and completeness of the information, investors should do their own research and may seek professional advice before investing.

Comments

We need your insight to fill this gap
Leave a comment