Movement Alert|AKESO Falls 3.03% in Regular Trading, positive ESMO biliary tract cancer data failed to offset post-placement pressure

Market Focus10-27

On October 27, AKESO fell 3.03% in Regular Trading, trading at HK$81.85, with turnover of HK$182 million.

The main recent catalyst in public information is that the company disclosed positive Phase III HARMONi-GI1 results for ivonescimab plus chemotherapy in first-line advanced biliary tract cancer, with the study selected for an ESMO Presidential Symposium oral presentation. The randomized, controlled, double-blind registrational trial enrolled 682 patients, and the indication had previously been proposed for priority review.

However, the stock has remained under pressure after the company completed a placement of 20 million new shares at HK$97.76 each, raising net proceeds of about HK$1.941 billion. The new shares represented about 2.13% of enlarged share capital, and the dilution and financing overhang appear to have limited the market reaction to the clinical update.

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