HENLIUS (02696) saw its shares rise over 4% in the afternoon session. At the time of writing, the stock was up 3.19%, trading at HK$69.65 with a turnover of HK$37.252 million.
The increase follows the company's announcement regarding its self-developed innovative anti-PD-1 monoclonal antibody, H drug Hansizhuang® (serplulimab, European brand name: Hetronifly®). The bridging trial in Japan for the first-line treatment of extensive-stage small cell lung cancer has completed patient enrollment.
This bridging trial, designated NCT06812260, aims to evaluate the efficacy and safety of the H drug combined with chemotherapy as a first-line treatment for ES-SCLC in Japanese patients. The study is led by Professor Takayasu Kurata from the Kansai Medical University Hospital.
The data from trial NCT06812260, along with results from the ASTRUM-005 study which supported the drug's approval in China and Europe for ES-SCLC, will form the key clinical evidence for the drug's registration application in the Japanese market. HENLIUS plans to collaborate with its Japanese partner, Eisai, to submit the marketing application during Eisai's 2026 fiscal year.
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