Clover Bio-B's stock surged 6.99% during intraday trading on Wednesday, following the release of encouraging clinical trial results for its respiratory syncytial virus (RSV) vaccine candidate.
The company reported additional Phase I data from a U.S. study showing that its SCB-1019 vaccine, when used as a heterologous booster in adults aged 60-85, generated approximately 60-80% higher geometric mean titers of RSV-A and RSV-B neutralizing antibodies compared to a booster dose of GSK's established vaccine, Arexvy. An exploratory analysis also suggested SCB-1019 restored antibody levels to 120-135% of the peak seen after an initial Arexvy dose, outperforming the homologous Arexvy booster.
With over 40% of eligible U.S. adults having received an initial RSV vaccine dose, the data positions Clover's candidate in a potential revaccination market. The company also noted its RSV combination vaccine candidates have progressed to Phase II trials, broadening their potential protective scope.
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