United Therapeutics, Kiniksa take off on pig-to-human heart transplant

Seeking Alpha2022-01-11

In a last-ditch effort to save his life, doctors at the University of Maryland Medical Center have transplanted a genetically modified pig heart into patient David Bennett, a 57-year-old handyman from...

Source Link

Disclaimer: Investing carries risk. This is not financial advice. The above content should not be regarded as an offer, recommendation, or solicitation on acquiring or disposing of any financial products, any associated discussions, comments, or posts by author or other users should not be considered as such either. It is solely for general information purpose only, which does not consider your own investment objectives, financial situations or needs. TTM assumes no responsibility or warranty for the accuracy and completeness of the information, investors should do their own research and may seek professional advice before investing.

Comments

BigThumb
2022-01-11
BigThumb
Wow! [Gosh]
chqngchang
2022-01-11
chqngchang
[Happy]
Andersonkana
2022-01-11
Andersonkana
nice
SiewMailing
2022-01-11
SiewMailing
Like
mutualtrader
2022-01-11
mutualtrader
Like please
Kakamaya
2022-01-11
Kakamaya
Oh

Leave a comment

{"i18n":{"language":"en_US"},"isChannel":false,"data":{"share":"https://ttm.financial/m/news/1194794619?lang=en_US&edition=fundamental","thumbnail":"","is_english":true,"pubTime":"2022-01-11 18:02","share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","id":"1194794619","market":"us","top_or_hot":-1,"title":"United Therapeutics, Kiniksa take off on pig-to-human heart transplant","media":"Seeking Alpha","content":"<div>\n<p>In a last-ditch effort to save his life, doctors at the University of Maryland Medical Center have transplanted a genetically modified pig heart into patient David Bennett, a 57-year-old handyman from...</p>\n\n<a href=\"https://seekingalpha.com/news/3786925-united-therapeutics-kiniksa-take-off-on-pig-to-human-heart-transplant\">Source Link</a>\n\n</div>\n","source":null,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>United Therapeutics, Kiniksa take off on pig-to-human heart transplant</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nUnited Therapeutics, Kiniksa take off on pig-to-human heart transplant\n</h2>\n\n<h4 class=\"meta\">\n\n\n2022-01-11 18:02 GMT+8&nbsp;&nbsp;&nbsp;<a href=https://seekingalpha.com/news/3786925-united-therapeutics-kiniksa-take-off-on-pig-to-human-heart-transplant><strong>Seeking Alpha</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>In a last-ditch effort to save his life, doctors at the University of Maryland Medical Center have transplanted a genetically modified pig heart into patient David Bennett, a 57-year-old handyman from...</p>\n\n<a href=\"https://seekingalpha.com/news/3786925-united-therapeutics-kiniksa-take-off-on-pig-to-human-heart-transplant\">Source Link</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"UTHR","symbol_name":"美国联合医疗","start_time":0,"source_url":"https://seekingalpha.com/news/3786925-united-therapeutics-kiniksa-take-off-on-pig-to-human-heart-transplant","article_id":"1194794619","we_media_id":null,"thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=1194794619","pubTimestamp":1641895360,"sourceInfo":null,"weMediaInfo":null,"summary":"In a last-ditch effort to save his life, doctors at the University of Maryland Medical Center have t","collect":0,"end_time":0,"defaultTopTitle":"seekingalpha.com","property":[],"viewcount":null,"language":"en","relate_stocks":{"UTHR":"美国联合医疗","KNSA":"Kiniksa Pharmaceuticals Ltd."},"translate_title":"联合治疗公司Kiniksa在猪-人心脏移植上起飞","themeId":"","isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"KNSA":0.9,"UTHR":0.9},"content_text":"In a last-ditch effort to save his life, doctors at the University of Maryland Medical Center have transplanted a genetically modified pig heart into patient David Bennett, a 57-year-old handyman from Maryland. He's doing well three days after the highly experimental surgery - and is being monitored for immune system problems and other complications - but it's still too early to tell if the operation will work. Due to his condition, Bennett had also received a pig heart valve about a decade ago, which (along with pig skin grafts) are routinely used in humans.Snapshot: \"It was either die or do this transplant. I want to live. I know it's a shot in the dark, but it's my last choice,\" Bennett said a day before the nine-hour surgery. While he knew there was no guarantee the experiment would be effective, Bennett was ineligible for a human heart transplant or pump due to heart failure condition and an irregular heartbeat. The FDA, which oversees such experiments, allowed the xenotransplantation surgery under \"compassionate use\" emergency authorization, which is available when a patient with a life-threatening condition has no other options.\"If this works, there will be an endless supply of these organs for patients who are suffering,\" said Dr. Muhammad Mohiuddin, scientific director of the University of Maryland's animal-to-human transplant program. A total of 106,657 people are currently on the national transplant waiting list, and more than 6,200 patients die each year before getting one. More than 40,000 organ transplants were done in the U.S. in 2021, including a record 3,800 heart transplants.New gene editing tools: Several biotech companies are developing pig organs for human transplant, with the heart used in the most recent operation coming from Revivicor, a subsidiary of United Therapeutics . The organ was modified to make it more acceptable to a human, including removing and inserting 10 genes to keep the heart from growing after transplant among other changes. The team at the University of Maryland Medical Center also used a new drug made by Kiniksa Pharmaceuticals  to help prevent the organ from being rejected by the patient.","kind":null,"is_publish_news":true,"is_publish_highlight":true,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"0","news_tag":"","news_rank":0,"symbols":[],"gpt_button":1},"commentList":[{"id":9002971423,"gmtCreate":1641906279545,"gmtModify":1676533660400,"author":{"id":"3581996485604595","authorId":"3581996485604595","name":"BigThumb","avatar":"https://static.tigerbbs.com/d9366427dbceb4a03b5342d31b6c3aaa","vip":1,"crmLevel":2,"crmLevelSwitch":0,"idStr":"3581996485604595","authorIdStr":"3581996485604595"},"htmlText":"Wow! [Gosh]&nbsp;","listText":"Wow! [Gosh]&nbsp;","text":"Wow! [Gosh]","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/9002971423","repostId":1194794619,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"EN"},{"id":9002950307,"gmtCreate":1641897972656,"gmtModify":1676533659744,"author":{"id":"3582358454168309","authorId":"3582358454168309","name":"chqngchang","avatar":"https://static.tigerbbs.com/b56233832049ceeac966ba711e0e1f75","vip":1,"crmLevel":3,"crmLevelSwitch":0,"idStr":"3582358454168309","authorIdStr":"3582358454168309"},"htmlText":"[Happy]&nbsp;","listText":"[Happy]&nbsp;","text":"[Happy]","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":2,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/9002950307","repostId":1194794619,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"EN"},{"id":9002924439,"gmtCreate":1641897728204,"gmtModify":1676533659736,"author":{"id":"4088599389256890","authorId":"4088599389256890","name":"Andersonkana","avatar":"https://static.tigerbbs.com/21e08c99709245ba5acdcf7245d9c40f","vip":1,"crmLevel":1,"crmLevelSwitch":0,"idStr":"4088599389256890","authorIdStr":"4088599389256890"},"htmlText":"&nbsp;nice","listText":"&nbsp;nice","text":"nice","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/9002924439","repostId":1194794619,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"EN"},{"id":9002921871,"gmtCreate":1641896024811,"gmtModify":1676533659584,"author":{"id":"4098273802374380","authorId":"4098273802374380","name":"SiewMailing","avatar":"https://static.laohu8.com/default-avatar.jpg","vip":1,"crmLevel":3,"crmLevelSwitch":0,"idStr":"4098273802374380","authorIdStr":"4098273802374380"},"htmlText":"Like","listText":"Like","text":"Like","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":5,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/9002921871","repostId":1194794619,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"EN"},{"id":9002921087,"gmtCreate":1641895926300,"gmtModify":1676533659567,"author":{"id":"3586395777619036","authorId":"3586395777619036","name":"mutualtrader","avatar":"https://static.laohu8.com/default-avatar.jpg","vip":1,"crmLevel":2,"crmLevelSwitch":0,"idStr":"3586395777619036","authorIdStr":"3586395777619036"},"htmlText":"Like please","listText":"Like please","text":"Like please","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":3,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/9002921087","repostId":1194794619,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"EN"},{"id":9002923863,"gmtCreate":1641895646649,"gmtModify":1676533659552,"author":{"id":"4090667763010140","authorId":"4090667763010140","name":"Kakamaya","avatar":"https://static.tigerbbs.com/ea7f11d12596522b325316b94f0e8077","vip":1,"hat":"https://static.tigerbbs.com/f84d87792f02cf78e80ee34979fd31e5","crmLevel":3,"crmLevelSwitch":1,"idStr":"4090667763010140","authorIdStr":"4090667763010140"},"htmlText":"Oh","listText":"Oh","text":"Oh","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":7,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/9002923863","repostId":1194794619,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"EN"}],"isCommentEnd":false,"newsSizeData":{"likeSize":49,"commentSize":6,"repostSize":0,"favoriteSize":0,"likeStatus":false,"favoriteStatus":false},"APP":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)","isDev":false,"isTTM":true,"deviceId":"web-server-community-laohu8-v3","version":"4.29.2","shortVersion":"4.29.2","platform":"web","vendor":"web","appName":"ttm","isIOS":false,"isAndroid":false,"isTiger":false,"isTHS":false,"isWeiXin":false,"isWeiXinMini":false,"isWeiBo":false,"isQQ":false,"isBaiduSwan":false,"isBaiduBox":false,"isDingTalk":false,"isToutiao":false,"isOnePlus":false,"isHuaWei":false,"isXiaomi":false,"isXiaomiWebView":false,"isOppo":false,"isVivo":false,"isSamsung":false,"isMobile":false},"href":"/m/news/1194794619"}