Novocure falls after setback to Phase 3 trial for Tumor Treating Fields

seekingalpha2023-08-28

NovoCure (NASDAQ:NVCR) lost ~39% pre-market Monday after the medical device maker announced that its cancer treatment, Tumor Treating Fields (TTFieds), didn't reach the main goal of overall survival (...

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L N Ramesh
2023-08-28
L N Ramesh
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The ENGOT-ov50 / GOG-3029 / INNOVATE-3 study, designed to evaluate TTFields in combination with chemotherapy paclitaxel in platinum-resistant ovarian cancer, had recruited 540 patients as of October 2021 when its enrollments closed.  According to its final data analysis, the patients on TTFields plus paclitaxel (n = 280) indicated a median OS of 12.2 months compared to 11.9 months of median OS in the paclitaxel-only arm (n = 278). The company said that the experimental therapy was well tolerated with no added systemic toxicities, in line with prior studies. However, citing an exploratory subgroup analysis, NovoCure (NVCR) stated that there was a clinical benefit for those who had previously received a single line of therapy. This finding \"suggests the potential for a clinical benefit when TTFields therapy is initiated early in a patient's treatment journey,\" Novocure's (NVCR) Executive Chairman William Doyle added.    More on NovoCure  NovoCure Limited: Record Losses, Falling Margins, And Downward Momentum NovoCure: Uncertain Regulatory Path And Slowing Growth  NovoCure Limited (NVCR) Q2 2023 Earnings Call Transcript NovoCure Limited 2023 Q2 - Results - Earnings Call Presentation NovoCure upgraded at Piper Sandler ahead of Phase 3 readout for TTFieds NovoCure upgraded at Wedbush citing balanced risk-reward setup Why did NovoCure stock crash today? TTFields data","kind":null,"is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"0","news_tag":"","news_rank":0,"symbols":[],"gpt_button":1},"commentList":[{"id":213843038212352,"gmtCreate":1693225836103,"gmtModify":1693225845792,"author":{"id":"4096514301867030","authorId":"4096514301867030","authorIdStr":"4096514301867030","name":"L N Ramesh","avatar":"https://static.laohu8.com/default-avatar.jpg","vip":1,"crmLevel":8,"crmLevelSwitch":1,"idStr":"4096514301867030"},"htmlText":"Share your opinion about this news…","listText":"Share your opinion about this news…","text":"Share your opinion about this news…","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://ttm.financial/post/213843038212352","repostId":2362124728,"repostType":2,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"EN"}],"isCommentEnd":false,"newsSizeData":{"likeSize":0,"commentSize":1,"repostSize":1,"favoriteSize":0,"likeStatus":false,"favoriteStatus":false},"APP":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)","isDev":false,"isTTM":true,"deviceId":"web-server-community-laohu8-v3","version":"4.28.3","shortVersion":"4.28.3","platform":"web","vendor":"web","appName":"ttm","isIOS":false,"isAndroid":false,"isTiger":false,"isTHS":false,"isWeiXin":false,"isWeiXinMini":false,"isWeiBo":false,"isQQ":false,"isBaiduSwan":false,"isBaiduBox":false,"isDingTalk":false,"isToutiao":false,"isOnePlus":false,"isHuaWei":false,"isXiaomi":false,"isXiaomiWebView":false,"isOppo":false,"isVivo":false,"isSamsung":false,"isMobile":false},"href":"/m/news/2362124728"}