** Hong Kong shares of WuXi AppTec drop as much as 14% to HK$44, their biggest intraday pct drop since since March 7
** Stock on course for a second session of falls, and is biggest pct loser in Hang Seng Index , Hang Seng Composite Index and Hang Seng Commerce & Industry Index
** Shanghai stock drops 8.6% to 51.88 yuan, lowest since March 11
** Washington-based Biotechnology Innovation Organization $(BIO)$, a global trade association representing biotechnology companies, is taking steps to "separate" from Chinese member Wuxi AppTec, according to a letter from its new CEO on Wednesday
** WuXi AppTec, in a letter to BIO dated Tuesday that it provided to Reuters, said it was ending its membership in the organization
** Shares of WuXi Biologics fall 12.3% to HK$16.22, their lowest since Feb 16
** WuXi XDC , a unit of WuXi Biologics, drops 15.5% to HK$16.70, its lowest since Feb 21
** Hang Seng Commerce & Industry Index eases 0.7%, while Seng Composite Index and Hang Seng Index each slip 0.9%
** WuXi AppTec's Hong Kong stock fell 43.7% YTD, Shanghai shares down 27.3% YTD
(Reporting by Donny Kwok)
((donny.kwok@thomsonreuters.com))
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