By Connor Hart
Neurocrine Biosciences said its trial of luvadaxistat as a potential treatment to improve cognitive impairment in patients with schizophrenia failed to meet its primary endpoint.
The San Diego biopharmaceutical company said Thursday that a recent study failed to replicate the cognitive endpoints data observed in an earlier study, due in part to the large variability seen in the cognitive measures across the population studied, as well as a potential imbalance in the baseline characteristics of subjects.
Chief Medical Officer Eiry Roberts said the company, as a result, plans to halt further development of luvadaxistat and switch focus to a different potential treatment for schizophrenia, as well as a potential treatment for major depressive disorder.
Shares were down 2.3% to $118.50 in after-hours trading.
Write to Connor Hart at connor.hart@wsj.com
(END) Dow Jones Newswires
September 12, 2024 16:33 ET (20:33 GMT)
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