Galapagos NV (GLPG) Q3 2024 Earnings Call Highlights: Strong Cash Position and R&D Progress ...

GuruFocus.com11-01 15:03

Cash Position: EUR3.3 billion at the end of September 2024. Net Profit: EUR49 million for the first nine months of 2024. Interest Income: EUR71 million. Net Profit from Discontinued Operations: EUR69 ...

Source Link

Disclaimer: Investing carries risk. This is not financial advice. The above content should not be regarded as an offer, recommendation, or solicitation on acquiring or disposing of any financial products, any associated discussions, comments, or posts by author or other users should not be considered as such either. It is solely for general information purpose only, which does not consider your own investment objectives, financial situations or needs. TTM assumes no responsibility or warranty for the accuracy and completeness of the information, investors should do their own research and may seek professional advice before investing.

Comments

We need your insight to fill this gap

Leave a comment

{"i18n":{"language":"en_US"},"isChannel":false,"data":{"share":"https://ttm.financial/m/news/2480024768?lang=en_US&edition=fundamental","thumbnail":"https://s.yimg.com/uu/api/res/1.2/gkxtGOPh2r.DuYWLFMJU9g--~B/aD00MDA7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/us.finance.gurufocus/a06ac4cc19c53956a0db3816bd7d081a","is_english":true,"pubTime":"2024-11-01 15:03","share_image_url":"https://static.laohu8.com/5f26f4a48f9cb3e29be4d71d3ba8c038","id":"2480024768","market":"us","top_or_hot":-1,"title":"Galapagos NV (GLPG) Q3 2024 Earnings Call Highlights: Strong Cash Position and R&D Progress ...","media":"GuruFocus.com","content":"<div>\n<p>Cash Position: EUR3.3 billion at the end of September 2024.\nNet Profit: EUR49 million for the first nine months of 2024.\nInterest Income: EUR71 million.\nNet Profit from Discontinued Operations: EUR69 ...</p>\n\n<a href=\"https://finance.yahoo.com/news/galapagos-nv-glpg-q3-2024-070324741.html\">Source Link</a>\n\n</div>\n","source":"yahoofinance","html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Galapagos NV (GLPG) Q3 2024 Earnings Call Highlights: Strong Cash Position and R&D Progress ...</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nGalapagos NV (GLPG) Q3 2024 Earnings Call Highlights: Strong Cash Position and R&D Progress ...\n</h2>\n\n<h4 class=\"meta\">\n\n\n2024-11-01 15:03 GMT+8&nbsp;&nbsp;&nbsp;<a href=https://finance.yahoo.com/news/galapagos-nv-glpg-q3-2024-070324741.html><strong>GuruFocus.com</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>Cash Position: EUR3.3 billion at the end of September 2024.\nNet Profit: EUR49 million for the first nine months of 2024.\nInterest Income: EUR71 million.\nNet Profit from Discontinued Operations: EUR69 ...</p>\n\n<a href=\"https://finance.yahoo.com/news/galapagos-nv-glpg-q3-2024-070324741.html\">Source Link</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"GLPG","symbol_name":"Galapagos NV","start_time":0,"source_url":"https://finance.yahoo.com/news/galapagos-nv-glpg-q3-2024-070324741.html","article_id":"2480024768","we_media_id":null,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/gkxtGOPh2r.DuYWLFMJU9g--~B/aD00MDA7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/us.finance.gurufocus/a06ac4cc19c53956a0db3816bd7d081a"],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2480024768","pubTimestamp":1730444604,"sourceInfo":{"source_id":"yahoofinance","name":"雅虎金融"},"weMediaInfo":null,"summary":"Cash Position: EUR3.3 billion at the end of September 2024.Net Profit: EUR49 million for the first nine months of 2024.Net Profit from Discontinued Operations: EUR69 million, mainly from the Jyseleca transaction.Cash Burn Guidance: EUR370 million to EUR410 million for 2024.Net Decrease in Cash Position: EUR346 million for the first nine months of 2024.Operational Cash Burn: EUR321 million, including EUR80 million related to business development activities.GuruFocus has detected 6 Warning Signs with GLPG.For the complete transcript of the earnings call, please refer to the full earnings call transcript.The company received IND clearance from the FDA for GLPG-5101, marking significant regulatory progress.Galapagos NV  is advancing its R&D pipeline with four clinical candidates for 11 indications and over 15 preclinical programs.The company is expanding its decentralized CAR-T manufacturing network in the US and Europe, enhancing operational capabilities.","collect":0,"end_time":0,"defaultTopTitle":"yahoo.com","property":["earning"],"viewcount":null,"language":"en","relate_stocks":{"GLPG":"Galapagos NV","PRGS":"Progress Software Corporation"},"translate_title":"Galapagos NV(GLPG)2024年第三季度收益看涨期权亮点：强劲的现金状况和研发进展……","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"GLPG":1,"PRGS":1},"content_text":"Cash Position: EUR3.3 billion at the end of September 2024.\nNet Profit: EUR49 million for the first nine months of 2024.\nInterest Income: EUR71 million.\nNet Profit from Discontinued Operations: EUR69 million, mainly from the Jyseleca transaction.\nCash Burn Guidance: EUR370 million to EUR410 million for 2024.\nNet Decrease in Cash Position: EUR346 million for the first nine months of 2024.\nOperational Cash Burn: EUR321 million, including EUR80 million related to business development activities.\n\n\nWarning! GuruFocus has detected 6 Warning Signs with GLPG.\n\nRelease Date: October 31, 2024\nFor the complete transcript of the earnings call, please refer to the full earnings call transcript.\n Positive Points \n\nGalapagos NV (NASDAQ:GLPG) has a strong cash position of EUR3.3 billion, supporting its pipeline development.\nThe company received IND clearance from the FDA for GLPG-5101, marking significant regulatory progress.\nGalapagos NV (NASDAQ:GLPG) is advancing its R&D pipeline with four clinical candidates for 11 indications and over 15 preclinical programs.\nThe company is expanding its decentralized CAR-T manufacturing network in the US and Europe, enhancing operational capabilities.\nGalapagos NV (NASDAQ:GLPG) reported a net profit of EUR49 million for the first nine months of 2024, driven by fair value adjustments and interest income.\n\n Negative Points \n\nIncreased R&D costs are impacting financials, driven by investments in oncology and collaborations.\nThe company faces challenges in the competitive CAR-T therapy market, particularly with BCMA-targeted therapies.\nThere is uncertainty regarding the timeline for potential market entry of CAR-T programs, dependent on regulatory processes.\nGalapagos NV (NASDAQ:GLPG) is experiencing a cash burn, with a net decrease of EUR346 million in cash position over the first nine months of 2024.\nThe company is still in the early stages of its pipeline development, with many programs yet to reach clinical trials.\n\n Q & A Highlights \nQ: Can you provide insights on the BCMA CAR-T 301 trial and any changes in future enrollment criteria? A: Paulus Stoffels, CEO, explained that BCMA-targeted CAR-T therapies can lead to Parkinson's due to BCMA expression in the brain. The company has conducted thorough due diligence and incorporated findings into the protocol, ensuring expansive discussions between medical monitors and investigators to address patient safety.\nQ: What details can you share about the data to be presented at ASH for EUPLAGIA and ATALANTA? A: Paulus Stoffels, CEO, stated that due to the ASH embargo, details cannot be disclosed until November 5. The company looks forward to sharing the data once the embargo is lifted.\nQ: What is your approach to business development next year, and what types of deals are you open to? A: Paulus Stoffels, CEO, mentioned that Galapagos is focused on oncology and immunology, particularly precision oncology and CAR-T opportunities. The company aims to leverage its strong cash position to broaden its portfolio.\nQ: Is there potential for your CAR-T programs, particularly F101, to enter the market earlier, and how confident are you in obtaining breakthrough therapy designation? A: Paulus Stoffels, CEO, noted that the company plans to include the first patient in the study by year-end and expand to other centers next year. They are confident in the data's strength and will follow the scientific and regulatory process to determine timelines.\nQ: Have you run any test runs for GLPG-5101 since the IND clearance, and are there any barriers specific to the US clinical infrastructure? A: Thad Huston, CFO and COO, confirmed no concerns regarding the median seven-day vein-to-vein time. The approach is consistent across the US and Europe, with productive interactions with the FDA providing important insights.\nQ: Can you provide more information on the new bispecific CAR-T advancing into IND-enabling studies? A: Paulus Stoffels, CEO, explained that the bispecific CAR-T addresses CD19 escape, a resistance issue. The preclinical data is promising, and more details will be shared during an R&D day next year.\nQ: Are you still prioritizing CAR-T for autoimmune diseases, and what is your approach to program prioritization? A: Paulus Stoffels, CEO, stated that while the field is crowded, they are interested in B-cell depletion mechanisms and will carefully choose when to step in with best-in-class products.\nQ: Can you provide more color on the TYK2 program and its timelines? A: Wulf Bocher, Head of Immunology, confirmed that the Phase 2 studies in dermatomyositis and lupus are progressing well, with data expected in 2025 and 2026. The TYK2 inhibitor is differentiated by preserving the IL-10 pathway, which is crucial for regulatory T cell differentiation.\nFor the complete transcript of the earnings call, please refer to the full earnings call transcript.This article first appeared on \nGuruFocus.","kind":null,"is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"0","news_tag":"","news_rank":0,"symbols":[],"gpt_button":1},"commentList":[],"isCommentEnd":true,"newsSizeData":{"likeSize":0,"commentSize":0,"repostSize":0,"favoriteSize":0,"likeStatus":false,"favoriteStatus":false},"APP":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)","isDev":false,"isTTM":true,"deviceId":"web-server-community-laohu8-v3","version":"4.29.1","shortVersion":"4.29.1","platform":"web","vendor":"web","appName":"ttm","isIOS":false,"isAndroid":false,"isTiger":false,"isTHS":false,"isWeiXin":false,"isWeiXinMini":false,"isWeiBo":false,"isQQ":false,"isBaiduSwan":false,"isBaiduBox":false,"isDingTalk":false,"isToutiao":false,"isOnePlus":false,"isHuaWei":false,"isXiaomi":false,"isXiaomiWebView":false,"isOppo":false,"isVivo":false,"isSamsung":false,"isMobile":false},"href":"/m/news/2480024768"}