Acurx Pharmaceuticals, Inc. Reports Third Quarter 2024 Results and Provides Business Update

PR Newswire11-13

STATEN ISLAND, N.Y., Nov. 13, 2024 /PRNewswire/ -- Acurx Pharmaceuticals, Inc. (NASDAQ: ACXP) ("we" or "Acurx" or the "Company"), a late-stage biopharmaceutical company developing a new class of ...

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(NASDAQ: ACXP) (\"we\" or \"Acurx\" or the \"Company\"), a late-stage biopharmaceutical company developing a new class of ...</p>\n\n<a href=\"https://finance.yahoo.com/news/acurx-pharmaceuticals-inc-reports-third-120000114.html\">Source Link</a>\n\n</div>\n","source":"yahoofinance","html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Acurx Pharmaceuticals, Inc. Reports Third Quarter 2024 Results and Provides Business Update</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nAcurx Pharmaceuticals, Inc. Reports Third Quarter 2024 Results and Provides Business Update\n</h2>\n\n<h4 class=\"meta\">\n\n\n2024-11-13 20:00 GMT+8&nbsp;&nbsp;&nbsp;<a href=https://finance.yahoo.com/news/acurx-pharmaceuticals-inc-reports-third-120000114.html><strong>PR Newswire</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>STATEN ISLAND, N.Y., Nov. 13, 2024 /PRNewswire/ -- Acurx Pharmaceuticals, Inc. (NASDAQ: ACXP) (\"we\" or \"Acurx\" or the \"Company\"), a late-stage biopharmaceutical company developing a new class of ...</p>\n\n<a href=\"https://finance.yahoo.com/news/acurx-pharmaceuticals-inc-reports-third-120000114.html\">Source Link</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"VRE","symbol_name":"Veris Residential","start_time":0,"source_url":"https://finance.yahoo.com/news/acurx-pharmaceuticals-inc-reports-third-120000114.html","article_id":"2483091990","we_media_id":null,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/jZTlKjgzq39AhhwD0Ujy9Q--~B/aD0xNjt3PTE2O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/prnewswire.com/0acee424d62555a0f2cf4b64e1517f23"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/acurx-pharmaceuticals-inc-reports-third-120000114.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"url":"https://stock-news.laohu8.com/highlight/detail?id=2483091990","pubTimestamp":1731499200,"sourceInfo":{"source_id":"yahoofinance","name":"雅虎金融"},"weMediaInfo":null,"summary":"STATEN ISLAND, N.Y., Nov. 13, 2024 /PRNewswire/ -- Acurx Pharmaceuticals, Inc.  , a late-stage biopharmaceutical company developing a new class of antibiotics for difficult-to-treat bacterial infections, announced today certain financial and operational results for the third quarter ended September 30, 2024.Highlights of the third quarter ended September 30, 2024, or in some cases shortly thereafter, include:. Also in July 2024, and very timely given our late-stage development progress, the USPTO  granted Acurx a new patent for ibezapolstat which specifically encompasses the \"treatment of C. difficile Infection while reducing recurrence of infection and improving the health of the gut microbiome\". This patent expires in June 2042 and we believe will provide an important downstream competitive advantage.Additionally in September 2024, we announced that selected ACX-375 DNA pol IIIC analogues demonstrated in vitro activity against B. anthracis , which is a Bioterrorism Category A pathoge","collect":0,"end_time":0,"defaultTopTitle":"yahoo.com","property":[],"viewcount":null,"language":"en","relate_stocks":{"VRE":"Veris Residential","BK4194":"办公房地产投资信托","BK4563":"昨日强势股","BK4139":"生物科技","BK4539":"次新股","BK4135":"资产管理与托管银行","GAIN":"格拉德斯通投资","ACXP":"Acurx Pharmaceuticals, LLC*","EOT":"Eaton Vance National Municipal O"},"translate_title":"Acurx Pharmaceuticals,Inc.报告2024年第三季度业绩并提供业务更新","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"EOT":1,"GAIN":1,"VRE":1,"ACXP":0.9},"content_text":"STATEN ISLAND, N.Y., Nov. 13, 2024 /PRNewswire/ -- Acurx Pharmaceuticals, Inc. (NASDAQ: ACXP) (\"we\" or \"Acurx\" or the \"Company\"), a late-stage biopharmaceutical company developing a new class of antibiotics for difficult-to-treat bacterial infections, announced today certain financial and operational results for the third quarter ended September 30, 2024.\nHighlights of the third quarter ended September 30, 2024, or in some cases shortly thereafter, include:\n\nIn July 2024, results from the ibezapolstat (IBZ) Phase 2 clinical trial in patients with C. difficile Infection (CDI) were presented at the 17th Biennial Congress of the Anaerobe Society of the Americas by Taryn A. Eubank, PharmD, BCIDP, Research Assistant Professor, University of Houston College of Pharmacy delivered an oral presentation entitled: \"Clinical Efficacy of Ibezapolstat in CDI: Results from Phase 2 trials.\"\nAlso in July 2024, and very timely given our late-stage development progress, the USPTO (United States Patent and Trademark Office) granted Acurx a new patent for ibezapolstat which specifically encompasses the \"treatment of C. difficile Infection while reducing recurrence of infection and improving the health of the gut microbiome\". This patent expires in June 2042 and we believe will provide an important downstream competitive advantage.\nIn August 2024, we submitted our request to FDA for a meeting to review our manufacturing processes and specifications for drug substance and final product and packaging (a \"CMC Meeting\") in order to commence Phase 3 clinical trials. This FDA submission is customary and follows our successful End of Ph2 clinical meeting with FDA which confirmed our Ph3 clinical trial readiness. We anticipate convening a meeting with FDA regarding CMC in the fourth quarter.\nIn September 2024, a presentation was given by Executive Chairman, Bob DeLuccia, at the World Antimicrobial Resistance Scientific Congress held in Philadelphia. In his presentation at the Innovation Showcase session, he highlighted that we have a complete roadmap, not only for the required components of our phase 3 clinical program, but also what's required for ultimate filing of an NDA (or New Drug Application) which is to be followed by submissions for Marketing Authorizations in other countries around the world. He also presented an update on the Company's preclinical GPSS® (Gram Positive Selective Spectrum) program for systemic oral and IV treatment of other gram-positive infections including, MRSA, VRE and DRSP.\nAlso in September 2024, we participated at the 8th Annual C. Difficile Symposium (or ICDS) in Bled, Slovenia, which is the premier global scientific venue for the review of C. Difficile research. At the ICDS Meeting, two presentations were made on behalf of the Company.\nAdditionally in September 2024, we announced that selected ACX-375 DNA pol IIIC analogues demonstrated in vitro activity against B. anthracis (or Anthrax), which is a Bioterrorism Category A pathogen, including activity against ciprofloxacin-resistant Anthrax. This work was performed at two independent qualified laboratories including the University of Florida. Planning is underway for an Anthrax bioterrorism development program.\nIn October 2024, we participated at IDWeek in Los Angeles, the annual scientific conference of the Infectious Diseases Society of America. Drs. Kevin Garey and Taryn Eubank presented a scientific poster showing that in the Phase 2b clinical trial, ibezapolstat had comparable clinical cure and sustained clinical cure rates and safety profile to vancomycin. Also, 5 of 5 ibezapolstat patients who were followed for 3 months after end of treatment (EOT) experienced no recurrence. Ibezapolstat-treated patients showed decreased concentrations of fecal primary bile acids, and higher ratios of secondary to primary bile acids than vancomycin-treated patients.\nInternational regulatory filing initiatives will continue in Q4 2024.\n\nThird Quarter 2024 Financial Results\n\nCash Position:The Company ended the quarter with cash totaling $5.8 million, compared to $7.5 million as of December 31, 2023. During the third quarter, the Company raised additional proceeds under its ATM financing program, with gross proceeds of approximately $1.6 million.\nR&D Expenses:Research and development expenses for the three months ended September 30, 2024 were $1.2 million compared to $1.3 million for the three months ended September 30, 2023. The decrease was due primarily to an increase in manufacturing related costs during the quarter of $0.1 million, offset by a reduction in consulting fees of $0.2 million. For the nine months ended September 30, 2024 research & development expenses were $4.6 million compared to $4.1 million for the nine months ended September 30, 2023, an increase of $0.5 million primarily due to $0.9 million increase in manufacturing related costs, offset by $0.4 million decrease in consulting fees.\nG&A Expenses:General and administrative expenses for the three months ended September 30, 2024 were $1.6 million compared to $1.8 million for the three months ended September 30, 2023, a decrease of $0.2 million. The decrease was primarily due to $0.2 million increase in professional fees, a $0.1 million increase in compensation costs, offset by a $0.5 million decrease in non cash share-based compensation related costs. For the nine months ended September 30, 2024, general and administrative expenses were $6.7 million compared to $5.4 million for the nine months ended September 30, 2023, an increase of $1.3 million. The increase was primarily due to $1.1 million increase in professional fees and a $0.2 million increase in legal costs.\nNet Income/Loss:The Company reported a net loss of $2.8 million or $0.17 per diluted share for the three months ended September 30, 2024 compared to a net loss of $3.1 million or $0.24 per diluted share for the three months ended September 30, 2023, and a net loss of $11.3 million or $0.71 per share for the nine months ended September 30, 2024, compared to a net loss of $9.5 million or $0.77 per share for the nine months ended September 30, 2023 for the reasons previously mentioned. The Company had 16,770,378 shares outstanding as of September 30, 2024.\n\nConference Call\nAs previously announced, David P. Luci, President and Chief Executive Officer, and Robert G. Shawah, Chief Financial Officer, will host a conference call to discuss the results and provide a business update as follows:\n\n\n\n\nDate: \nWednesday, November 13, 2024 \n\n\nTime: \n8:00 a.m. ET \n\n\nToll free (U.S. and International): \n877-790-1503 \n\n\nConference ID: \n13749688 \n\n\n\n\nAbout Ibezapolstat\nIbezapolstat is the Company's lead antibiotic candidate preparing to advance to international Phase 3 clinical trials to treat patients with C. difficile Infection (CDI). Ibezapolstat is a novel, orally administered antibiotic being developed as a Gram-Positive Selective Spectrum (GPSS®) antibacterial. It is the first of a new class of DNA polymerase IIIC inhibitors under development by Acurx to treat bacterial infections. Ibezapolstat's unique spectrum of activity, which includes C. difficile but spares other Firmicutes and the important Actinobacteria phyla, appears to contribute to the maintenance of a healthy gut microbiome.\nIn June 2018, ibezapolstat was designated by the U.S. Food and Drug Administration (FDA) as a Qualified Infectious Disease Product (QIDP) for the treatment of patients with CDI and will be eligible to benefit from the incentives for the development of new antibiotics established under the Generating New Antibiotic Incentives Now (GAIN) Act. In January 2019, FDA granted \"Fast Track\" designation to ibezapolstat for the treatment of patients with CDI. The CDC has designated C. difficile as an urgent threat highlighting the need for new antibiotics to treat CDI.\nAbout Acurx Pharmaceuticals, Inc. \nAcurx Pharmaceuticals is a late-stage biopharmaceutical company focused on developing a new class of small molecule antibiotics for difficult-to-treat bacterial infections. The Company's approach is to develop antibiotic candidates with a Gram-positive selective spectrum (GPSS®) that blocks the active site of the Gram+ specific bacterial enzyme DNA polymerase IIIC (pol IIIC), inhibiting DNA replication and leading to Gram-positive bacterial cell death. Its R&D pipeline includes antibiotic product candidates that target Gram-positive bacteria, including Clostridioides difficile, methicillin-resistant Staphylococcus aureus (MRSA), vancomycin resistant Enterococcus (VRE) and drug-resistant Streptococcus pneumoniae (DRSP).\nTo learn more about Acurx Pharmaceuticals and its product pipeline, please visit www.acurxpharma.com.\nForward-Looking Statements \nAny statements in this press release about our future expectations, plans and prospects, including statements regarding our strategy, future operations, prospects, plans and objectives, and other statements containing the words \"believes,\" \"anticipates,\" \"plans,\" \"expects,\" and similar expressions, constitute forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including: whether ibezapolstat will benefit from the QIDP designation; whether ibezapolstat will advance through the clinical trial process on a timely basis; whether the results of the clinical trials of ibezapolstat will warrant the submission of applications for marketing approval, and if so, whether ibezapolstat will receive approval from the FDA or equivalent foreign regulatory agencies where approval is sought; whether, if ibezapolstat obtains approval, it will be successfully distributed and marketed; and other risks and uncertainties described in the Company's annual report filed with the Securities and Exchange Commission on Form 10-K for the year ended December 31, 2023, and in the Company's subsequent filings with the Securities and Exchange Commission. Such forward-looking statements speak only as of the date of this press release, and Acurx disclaims any intent or obligation to update these forward-looking statements to reflect events or circumstances after the date of such statements, except as may be required by law.\nInvestor Contact:\nAcurx Pharmaceuticals, Inc.David P. Luci, President & Chief Executive OfficerTel: 917-533-1469Email: davidluci@acurxpharma.com\n\n\n\n\nACURX PHARMACEUTICALS, INC. \n\n\n\n\n\nCONDENSED INTERIM BALANCE SHEETS \n\n\n\n\n\n\n\nSeptember 30,  \n\nDecember 31,  \n\n\n\n\n2024 \n\n2023 \n\n\n\n\n(unaudited) \n\n(Note 2) \n\n\nASSETS \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nCURRENT ASSETS \n\n\n\n\n\n\n\n\nCash \n\n$ \n5,762,564 \n\n$ \n7,474,188 \n\n\nOther Receivable  \n\n\n97,373 \n\n\n129,159 \n\n\nPrepaid Expenses \n\n\n122,822 \n\n\n105,776 \n\n\nTOTAL ASSETS \n\n$ \n5,982,759 \n\n$ \n7,709,123 \n\n\n\n\n\n\n\n\n\n\n\nLIABILITIES AND SHAREHOLDERS' EQUITY \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nCURRENT LIABILITIES \n\n\n\n\n\n\n\n\nAccounts Payable and Accrued Expenses \n\n$ \n3,318,765 \n\n$ \n3,042,438 \n\n\nTOTAL CURRENT LIABILITIES \n\n\n3,318,765 \n\n\n3,042,438 \n\n\n\n\n\n\n\n\n\n\n\nTOTAL LIABILITIES \n\n\n3,318,765 \n\n\n3,042,438 \n\n\n\n\n\n\n\n\n\n\n\nCOMMITMENTS AND CONTINGENCIES \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nSHAREHOLDERS' EQUITY \n\n\n\n\n\n\n\n\nCommon Stock; $.001 par value, 200,000,000 shares authorized, 16,770,378 and 14,468,229 shares issued and outstanding at September 30, 2024 and December 31, 2023, respectively \n\n\n16,770 \n\n\n14,468 \n\n\nAdditional Paid-In Capital \n\n\n67,187,389 \n\n\n57,871,070 \n\n\nAccumulated Deficit \n\n\n(64,540,165) \n\n\n(53,218,853) \n\n\n\n\n\n\n\n\n\n\n\nTOTAL SHAREHOLDERS' EQUITY \n\n\n2,663,994 \n\n\n4,666,685 \n\n\n\n\n\n\n\n\n\n\n\nTOTAL LIABILITIES AND SHAREHOLDERS' EQUITY \n\n$ \n5,982,759 \n\n$ \n7,709,123 \n\n\n\n\n\n\n\n\nACURX PHARMACEUTICALS, INC. \n\n\n\n\n\n\n\nCONDENSED INTERIM STATEMENTS OF OPERATIONS \n\n\n\n\n\n\n\n\n\nThree Months Ended  \n\nNine Months Ended  \n\n\n\n\n\nSeptember 30,  \n\nSeptember 30,  \n\n\n\n\n\n2024 \n\n2023 \n\n2024 \n\n2023 \n\n\n\n\n\n(unaudited) \n\n(unaudited) \n\n(unaudited) \n\n(unaudited) \n\n\n\nOPERATING EXPENSES \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nResearch and Development \n\n$ \n1,198,184 \n\n$ \n1,348,985 \n\n$ \n4,578,777 \n\n$ \n4,100,954 \n\n\n\nGeneral and Administrative \n\n\n1,623,413 \n\n\n1,765,996 \n\n\n6,742,535 \n\n\n5,362,224 \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nTOTAL OPERATING EXPENSES \n\n\n2,821,597 \n\n\n3,114,981 \n\n\n11,321,312 \n\n\n9,463,178 \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nNET LOSS \n\n$ \n(2,821,597) \n\n$ \n(3,114,981) \n\n$ \n(11,321,312) \n\n$ \n(9,463,178) \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nLOSS PER SHARE \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nBasic and diluted net loss per common share \n\n$ \n(0.17) \n\n$ \n(0.24) \n\n$ \n(0.71) \n\n$ \n(0.77) \n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\nWeighted average common shares outstanding, basic and diluted \n\n\n16,363,473 \n\n\n13,005,128 \n\n\n15,907,778 \n\n\n12,282,004 \n\n\n\n\n\n View original content:https://www.prnewswire.com/news-releases/acurx-pharmaceuticals-inc-reports-third-quarter-2024-results-and-provides-business-update-302303717.html\nSOURCE Acurx Pharmaceuticals, Inc.","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"0","news_tag":"","news_rank":0,"symbols":[],"gpt_button":0},"commentList":[],"isCommentEnd":true,"newsSizeData":{"likeSize":0,"commentSize":0,"repostSize":0,"favoriteSize":0,"likeStatus":false,"favoriteStatus":false},"APP":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)","isDev":false,"isTTM":true,"deviceId":"web-server-community-laohu8-v3","version":"4.29.3","shortVersion":"4.29.3","platform":"web","vendor":"web","appName":"ttm","isIOS":false,"isAndroid":false,"isTiger":false,"isTHS":false,"isWeiXin":false,"isWeiXinMini":false,"isWeiBo":false,"isQQ":false,"isBaiduSwan":false,"isBaiduBox":false,"isDingTalk":false,"isToutiao":false,"isOnePlus":false,"isHuaWei":false,"isXiaomi":false,"isXiaomiWebView":false,"isOppo":false,"isVivo":false,"isSamsung":false,"isMobile":false},"href":"/m/news/2483091990"}