GT Biopharma Reports Third Quarter 2024 Financial Results

GlobeNewswire11-15

GTB-3650 TriKE® Phase 1 trial first patient dosed expected in Q4 2024; initial clinical data expected in Q2 2025 GTB-5550 TriKE® IND submission for treatment of B7H3 positive solid tumors expected in ...

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overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nGT Biopharma Reports Third Quarter 2024 Financial Results\n</h2>\n\n<h4 class=\"meta\">\n\n\n2024-11-15 05:00 GMT+8&nbsp;&nbsp;&nbsp;<a href=https://finance.yahoo.com/news/gt-biopharma-reports-third-quarter-210000835.html><strong>GlobeNewswire</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>GTB-3650 TriKE® Phase 1 trial first patient dosed expected in Q4 2024; initial clinical data expected in Q2 2025\nGTB-5550 TriKE® IND submission for treatment of B7H3 positive solid tumors expected in ...</p>\n\n<a href=\"https://finance.yahoo.com/news/gt-biopharma-reports-third-quarter-210000835.html\">Source Link</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"GTBP","symbol_name":"GT Biopharma Inc.","start_time":0,"source_url":"https://finance.yahoo.com/news/gt-biopharma-reports-third-quarter-210000835.html","article_id":"2483332035","we_media_id":null,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/Sz9nU1F39_W72RyLi3qAbA--~B/aD05OTt3PTIxNTthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/globenewswire.com/c618aabc296a3a76b9d6362bead19496"],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2483332035","pubTimestamp":1731618000,"sourceInfo":{"source_id":"yahoofinance","name":"雅虎金融"},"weMediaInfo":null,"summary":"GTB-3650 TriKEPhase 1 trial first patient dosed expected in Q4 2024; initial clinical data expected in Q2 2025. GTB-5550 TriKEIND submission for treatment of B7H3 positive solid tumors expected in 1H 2025. GTB-5550 Phase 1 dose escalation basket trial initiation expected in 2025 evaluating multiple solid tumor types, including prostate, breast, head and neck, ovarian, lung, liver, and GI. GTB-7550 TriKEtargets CD19 and is in preclinical development for the treatment of Lupus and other autoimmune indications. The University of Minnesota, pursuant to its license agreement with GT Biopharma, is entitled to receive royalties should commercial sales of GTB-3650 be realized. This interest has been reviewed and managed by the University of Minnesota in accordance with its conflict of interest policies.","collect":0,"end_time":0,"defaultTopTitle":"yahoo.com","property":[],"viewcount":null,"language":"en","relate_stocks":{"GTBP":"GT Biopharma Inc.","BK4585":"ETF&股票定投概念","GT":"固特异轮胎橡胶公司","BK4139":"生物科技","BK4119":"轮胎与橡胶","BK4588":"碎股"},"translate_title":"GT Biopharma报告2024年第三季度财务业绩","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"GT":1,"GTBP":0.9},"content_text":"GTB-3650 TriKE® Phase 1 trial first patient dosed expected in Q4 2024; initial clinical data expected in Q2 2025\nGTB-5550 TriKE® IND submission for treatment of B7H3 positive solid tumors expected in 1H 2025\nGTB-5550 Phase 1 dose escalation basket trial initiation expected in 2025 evaluating multiple solid tumor types, including prostate, breast, head and neck, ovarian, lung, liver, and GI\nGTB-7550 TriKE® targets CD19 and is in preclinical development for the treatment of Lupus and other autoimmune indications\nCash of approximately $6.5 million as of September 30, 2024, anticipated to be sufficient to fund operations into Q2 2025\n\nSAN FRANCISCO, CALIFORNIA, Nov. 14, 2024 (GLOBE NEWSWIRE) -- GT Biopharma, Inc. (the “Company”) (NASDAQ: GTBP), a clinical stage immuno-oncology company focused on developing innovative therapeutics based on the Company's proprietary natural killer (NK) cell engager TriKE® platform, today announced third quarter 2024 financial results for the period ended September 30, 2024.\n“We are pleased to be progressing towards dosing the first patient in our Phase 1 trial evaluating GTB-3650 in cancer patients in the fourth quarter of this year. This dose escalation study will evaluate GTB-3650 in 12 patients (six cohorts) with relapsed or refractory (r/r) CD33 expressing hematologic malignancies, including refractory acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS). We believe that NK cell engagers, like GTB-3650, have the potential to offer patients with a safer alternative to current treatments, like CAR-T therapy”, said Michael Breen, Executive Chairman and interim Chief Executive Office of GT Biopharma.\nThis past October, the company held a virtual KOL event featuring Jeffrey Miller, MD1 and Mark Juckett, MD from the University of Minnesota Medical School2 who spoke to the value of NK cells within the broader therapeutic landscape as well as the potential for GT Biopharma’s NK cell engager pipeline, and specifically GTB-7550 which targets CD19 for autoimmune indications. “As a company, we are especially excited to continue exploring opportunities where our TriKE platform technology may have therapeutic utility, especially for autoimmune indications and in combination with NK cell therapies”, said Michael Breen. “In this rapidly emerging field, combination approaches may offer us the opportunity to leverage our patented platform technology across multiple NK cell engager constructs with new targets and for additional diseases.\n\nDr. Miller is the Consulting Senior Medical Director at GT Biopharma and holds stock and options in GTBP.\nThe University of Minnesota, pursuant to its license agreement with GT Biopharma, is entitled to receive royalties should commercial sales of GTB-3650 be realized. This interest has been reviewed and managed by the University of Minnesota in accordance with its conflict of interest policies.\n\nThird Quarter 2024 Financial Summary\nCash Position: The Company had cash and cash equivalents of approximately $6.5 million as of September 30, 2024, anticipated to be sufficient to fund operations into Q2 2025.\nResearch and Development (R&D) Expenses: R&D expenses for the third quarter ended September 30, 2024 were $1.3 million, flat compared to the same comparable quarter of 2023, primarily due to a reduction in raw material costs and partially offset by an increase in scientific research costs. Research and development expenses relate to our continued development and production of our most advanced TriKE® product candidates GTB-3650 and GTB-5550 along with the progression of other promising candidates. In late June 2024, we received clearance from the FDA with respect to its IND Application in relation to GTB 3650. We anticipate the direct clinical and preclinical expenses to increase in 2024 as we advance GTB-3650 into the clinic and enroll patients, perform tests for data collection, complete the product development of GTB-5550, and anticipate submission of an IND application for GTB-5550 in the first half of 2025. We do not, however, anticipate an increase in related R&D licensing and administrative costs.\nSelling, General and Administrative (SG&A) Expenses (Excluding Stock Compensation): SG&A expenses for the third quarter ended September 30, 2024 were $2.3 million compared to $1.2 million for the same comparable quarter of 2023, the $1.1 million increase was primarily due to an increase in legal and professional fees and for the probable settlement of a legal matter.\nOther Income: Other income for the third quarter ended September 30, 2024 was $193,000 compared to $706,000 for the same comparable quarter of 2023, the decrease was primarily due to a $390,000 reduction in the non-cash change in fair value of warrant liability.\nNet Loss: The Company reported a net loss of $3.4 million for the third quarter ended September 30, 2024 compared to a net loss of $2.4 million for the same comparable quarter in 2023. The $1 million increase in net loss consisted primarily of a $390,000 reduction in the non-cash change in fair value of warrant liability and a $1.2 million increase in SG&A expenses (as described above), partially offset by a $547,000 decrease in stock compensation expense.\nAbout GT Biopharma, Inc.\nGT Biopharma, Inc. is a clinical stage biopharmaceutical company focused on the development and commercialization of immuno-oncology therapeutic products based on our proprietary TriKE® NK cell engager platform. Our TriKE® platform is designed to harness and enhance the cancer killing abilities of a patient’s immune system’s natural killer cells. GT Biopharma has an exclusive worldwide license agreement with the University of Minnesota to further develop and commercialize therapies using TriKE® technology. For more information, please visit gtbiopharma.com.\nForward-Looking Statements\nCertain statements in this press release may constitute \"forward-looking statements\" regarding future events and our future results. All statements other than statements of historical facts are statements that could be deemed to be forward-looking statements. These statements are based on current expectations, estimates, forecasts, and projections about the markets in which we operate and the beliefs and assumptions of our management. Words such as \"expects,\" \"anticipates,\" \"targets,\" \"goals,\" \"projects\", \"intends,\" \"plans,\" \"believes,\" \"seeks,\" \"estimates,\" \"endeavors,\" \"strives,\" \"may,\" or variations of such words, and similar expressions are intended to identify such forward-looking statements. Readers are cautioned that these forward-looking statements are subject to a number of risks, uncertainties and assumptions that are difficult to predict, estimate or verify. Therefore, actual results may differ materially and adversely from those expressed in any forward-looking statements. Such risks and uncertainties include those factors described in our most recent annual report on Form 10-K, as such may be amended or supplemented by subsequent quarterly reports on Form 10-Q, or other reports filed with the Securities and Exchange Commission. Readers are cautioned not to place undue reliance on these forward-looking statements. The forward-looking statements are made only as of the date hereof, and we undertake no obligation to publicly release the result of any revisions to these forward-looking statements. For more information, please refer to our filings with the Securities and Exchange Commission.\nTriKE® is a registered trademark owned by GT Biopharma, Inc.\nInvestor Relations Contact:\nLifeSci AdvisorsCorey Davis, Ph.D.cdavis@lifesciadvisors.com212-915-2577 \nGT BIOPHARMA, INC. AND SUBSIDIARIESCondensed Consolidated Balance Sheets\n\n\n\n \n \nSeptember 30, 2024\n \n \nDecember 31, 2023\n \n\n\n \n \n \n(Unaudited)\n \n \n \n \n \n\n\nASSETS\n \n \n \n \n \n \n \n \n\n\nCurrent assets\n \n \n \n \n \n \n \n \n\n\nCash and cash equivalents\n \n$\n6,418,000\n \n \n$\n1,079,000\n \n\n\nRestricted cash\n \n \n93,000\n \n \n \n—\n \n\n\nShort-term investments\n \n \n—\n \n \n \n12,893,000\n \n\n\nPrepaid expenses and other current assets\n \n \n248,000\n \n \n \n84,000\n \n\n\nTotal Current Assets\n \n \n6,759,000\n \n \n \n14,056,000\n \n\n\n \n \n \n \n \n \n \n \n \n\n\nOperating lease right-of-use asset\n \n \n—\n \n \n \n53,000\n \n\n\nTOTAL ASSETS\n \n$\n6,759,000\n \n \n$\n14,109,000\n \n\n\n \n \n \n \n \n \n \n \n \n\n\nLIABILITIES AND STOCKHOLDERS’ EQUITY\n \n \n \n \n \n \n \n \n\n\nCurrent liabilities\n \n \n \n \n \n \n \n \n\n\nAccounts payable\n \n$\n2,612,000\n \n \n$\n4,328,000\n \n\n\nAccrued expenses\n \n \n1,868,000\n \n \n \n1,195,000\n \n\n\nCurrent operating lease liability\n \n \n—\n \n \n \n58,000\n \n\n\nWarrant liability\n \n \n182,000\n \n \n \n1,052,000\n \n\n\nTotal Current Liabilities\n \n \n4,662,000\n \n \n \n6,633,000\n \n\n\n \n \n \n \n \n \n \n \n \n\n\nStockholders’ Equity\n \n \n \n \n \n \n \n \n\n\nConvertible Preferred stock, par value $0.01, 15,000,000 shares authorized Series C - 96,230 shares issued and outstanding at September 30, 2024 and December 31, 2023, respectively\n \n \n1,000\n \n \n \n1,000\n \n\n\nCommon stock, par value $0.001, 250,000,000 shares authorized, 2,234,328 and 1,380,633 shares issued and outstanding as of September 30, 2024 and December 31, 2023, respectively\n \n \n2,000\n \n \n \n1,000\n \n\n\nAdditional paid in capital\n \n \n693,546,000\n \n \n \n689,539,000\n \n\n\nAccumulated deficit\n \n \n(691,452,000\n)\n \n \n(682,065,000\n)\n\n\nTotal Stockholders’ Equity\n \n \n2,097,000\n \n \n \n7,476,000\n \n\n\nTOTAL LIABILITIES AND STOCKHOLDERS’ EQUITY\n \n$\n6,759,000\n \n \n$\n14,109,000\n \n\n\n\nGT BIOPHARMA, INC. AND SUBSIDIARIESCondensed Consolidated Statements of Operations\n\n\n\n \n \nFor The Three Months Ended\n \n \nFor the Nine Months Ended\n \n\n\n \n \nSeptember 30,\n \n \nSeptember 30,\n \n\n\n \n \n2024\n \n \n2023\n \n \n2024\n \n \n2023\n \n\n\n \n \n(Unaudited)\n \n \n(Unaudited)\n \n \n(Unaudited)\n \n \n(Unaudited)\n \n\n\n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\nOperating Expenses:\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\nResearch and development\n \n$\n1,307,000\n \n \n$\n1,364,000\n \n \n$\n3,868,000\n \n \n$\n5,109,000\n \n\n\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\nSelling, general and administrative (including $0 and $547,000 from stock compensation granted to officers, directors, and employees and for services for the three months ended September 30, 2024 and 2023, respectively, and $222,000 and $1,767,000 for the nine months ended September 30, 2024 and 2023, respectively)\n \n \n2,297,000\n \n \n \n1,758,000\n \n \n \n6,733,000\n \n \n \n5,299,000\n \n\n\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\nLoss from Operations\n \n \n(3,604,000\n)\n \n \n(3,122,000\n)\n \n \n(10,601,000\n)\n \n \n(10,408,000\n)\n\n\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\nOther Income (Expense)\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\nInterest income\n \n \n96,000\n \n \n \n216,000\n \n \n \n343,000\n \n \n \n600,000\n \n\n\nInterest expense\n \n \n—\n \n \n \n—\n \n \n \n—\n \n \n \n(213,000\n)\n\n\nChange in fair value of warrant liability\n \n \n95,000\n \n \n \n485,000\n \n \n \n870,000\n \n \n \n4,796,000\n \n\n\nGain on extinguishment of debt\n \n \n—\n \n \n \n—\n \n \n \n—\n \n \n \n547,000\n \n\n\nUnrealized gain on marketable securities\n \n \n2,000\n \n \n \n5,000\n \n \n \n1,000\n \n \n \n43,000\n \n\n\nTotal Other Income, Net\n \n \n193,000\n \n \n \n706,000\n \n \n \n1,214,000\n \n \n \n5,773,000\n \n\n\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\nNet Loss\n \n$\n(3,411,000\n)\n \n$\n(2,416,000\n)\n \n$\n(9,387,000\n)\n \n$\n(4,635,000\n)\n\n\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\nNet Loss Per Share - Basic and Diluted\n \n$\n(1.53\n)\n \n$\n(1.77\n)\n \n$\n(5.28\n)\n \n$\n(3.47\n)\n\n\n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n \n\n\nWeighted average common shares outstanding - basic and diluted\n \n \n2,234,328\n \n \n \n1,367,206\n \n \n \n1,777,313\n \n \n \n1,336,532\n \n\n\n\nGT BIOPHARMA, INC. AND SUBSIDIARIESCondensed Consolidated Statements of Cash Flows\n\n\n\n \n \nFor The Nine Months Ended\n \n\n\n \n \nSeptember 30,\n \n\n\n \n \n2024\n \n \n2023\n \n\n\n \n \n(Unaudited)\n \n \n(Unaudited)\n \n\n\nCASH FLOWS FROM OPERATING ACTIVITIES\n \n \n \n \n \n \n \n \n\n\nNet loss\n \n$\n(9,387,000\n)\n \n$\n(4,635,000\n)\n\n\nAdjustments to reconcile net loss to net cash used in operating activities:\n \n \n \n \n \n \n \n \n\n\nStock based compensation – services\n \n \n—\n \n \n \n430,000\n \n\n\nStock based compensation - officers, directors, and employees\n \n \n222,000\n \n \n \n1,337,000\n \n\n\nChange in fair value of warrant liability\n \n \n(870,000\n)\n \n \n(4,796,000\n)\n\n\nGain on extinguishment of share settled debt\n \n \n—\n \n \n \n(547,000\n)\n\n\nChange in operating lease right-of-use assets\n \n \n53,000\n \n \n \n78,000\n \n\n\nUnrealized loss (gain) on marketable securities\n \n \n1,000\n \n \n \n(43,000\n)\n\n\nChanges in operating assets and liabilities:\n \n \n \n \n \n \n \n \n\n\nDecrease in prepaid expenses\n \n \n(164,000\n)\n \n \n16,000\n \n\n\nIncrease (Decrease) in accounts payable and accrued expenses\n \n \n(233,000\n)\n \n \n1,437,000\n \n\n\n(Decrease) in operating lease liability\n \n \n(58,000\n)\n \n \n(82,000\n)\n\n\nNet Cash Used in Operating Activities\n \n \n(10,436,000\n)\n \n \n(6,805,000\n)\n\n\n \n \n \n \n \n \n \n \n \n\n\nCASH FLOWS FROM INVESTING ACTIVITIES\n \n \n \n \n \n \n \n \n\n\nSale (Purchase) of investments\n \n \n12,892,000\n \n \n \n(2,487,000\n)\n\n\nNet Cash Provided by (Used in) Investing Activities\n \n \n12,892,000\n \n \n \n(2,487,000\n)\n\n\n \n \n \n \n \n \n \n \n \n\n\nCASH FLOWS FROM FINANCING ACTIVITIES\n \n \n \n \n \n \n \n \n\n\nProceeds from issuance of common stock and warrants, net\n \n \n2,976,000\n \n \n \n6,268,000\n \n\n\nNet Cash Provided by Financing Activities\n \n \n2,976,000\n \n \n \n6,268,000\n \n\n\n \n \n \n \n \n \n \n \n \n\n\nNet Increase (Decrease) in Cash and Cash Equivalents and Restricted Cash\n \n \n5,432,000\n \n \n \n(3,024,000\n)\n\n\nCash and Cash Equivalents and Restricted Cash at Beginning of Period\n \n \n1,079,000\n \n \n \n5,672,000\n \n\n\nCash and Cash Equivalents and Restricted Cash at End of Period\n \n$\n6,511,000\n \n \n$\n2,648,000\n \n\n\n \n \n \n \n \n \n \n \n \n\n\nSUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION:\n \n \n \n \n \n \n \n \n\n\nCash paid during the year for:\n \n \n \n \n \n \n \n \n\n\nInterest\n \n$\n—\n \n \n$\n—\n \n\n\nIncome taxes\n \n$\n—\n \n \n$\n—\n \n\n\n \n \n \n \n \n \n \n \n \n\n\nSUPPLEMENTAL DISCLOSURES OF NON-CASH INVESTING AND FINANCING ACTIVITIES\n \n \n \n \n \n \n \n \n\n\nInitial recognition of fair value of warrant liability\n \n$\n—\n \n \n$\n5,831,000\n \n\n\nFair value of common stock issued to a vendor to settle accounts payable\n \n$\n810,000\n \n \n$\n700,000","kind":null,"is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"0","news_tag":"","news_rank":0,"symbols":[],"gpt_button":0},"commentList":[],"isCommentEnd":true,"newsSizeData":{"likeSize":0,"commentSize":0,"repostSize":0,"favoriteSize":0,"likeStatus":false,"favoriteStatus":false},"APP":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)","isDev":false,"isTTM":true,"deviceId":"web-server-community-laohu8-v3","version":"4.29.2","shortVersion":"4.29.2","platform":"web","vendor":"web","appName":"ttm","isIOS":false,"isAndroid":false,"isTiger":false,"isTHS":false,"isWeiXin":false,"isWeiXinMini":false,"isWeiBo":false,"isQQ":false,"isBaiduSwan":false,"isBaiduBox":false,"isDingTalk":false,"isToutiao":false,"isOnePlus":false,"isHuaWei":false,"isXiaomi":false,"isXiaomiWebView":false,"isOppo":false,"isVivo":false,"isSamsung":false,"isMobile":false},"href":"/m/news/2483332035"}