** Brokerage Guggenheim downgrades drug developer Keros Therapeutics KROS.O to "neutral" from "buy"; removes PT on stock, previous PT was $102
** Says brokerage is "surprised" and "disappointed" after co paused higher doses of its experimental high blood pressure treatment "cibotercept" in a mid-stage study after reports of adverse effects on Thursday
** Shares were down ~73% at close on Thursday following the announcement
**Brokerage sees co and stock having a difficult path ahead, at least in near term
** Says exact reason for occurrence will likely wouldn't be clear until topline data is released in Q2 2025
** Also lowers cibotercept's probability of success, but still sees significant upside potential for the treatment if it demonstrates efficacy similar to Merck's MRK.N sotatercept
** 11 of 15 brokerages rate the stock "buy" or higher, and four "hold", with a median PT of $42
** Including session moves, stock has fallen ~52% YTD
(Reporting by Neil J Kanatt in Bengaluru)
((Neil.JKanatt@thomsonreuters.com;))
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