Innovent Bio Grants Roche Exclusive Global Rights to ADC Targeting DLL3

MT Newswires Live2025-01-02

Innovent Biologics (HKG:1801) granted Roche exclusive global rights to develop, manufacture, and sell IBI3009, a DLL3-targeted antibody-drug conjugate (ADC) candidate.

This collaboration aims to bring treatment options to patients with advanced small-cell lung cancer (SCLC), according to a Thursday filing with the Hong Kong Exchange.

Under the deal, Innovent and Roche will partner on the early-stage development of this ADC candidate, after which Roche will take over full development.

Innovent will receive $80 million in upfront payments and be eligible for up to $1 billion in milestone payments, along with tiered royalties on net sales, the filing stated.

IBI3009 targets DLL3, an antigen significantly overexpressed in certain cancers, particularly SCLC and other neuroendocrine tumors.

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