Portage Biotech Shares Rise on Confirmatory Trial Results, Plans for Human Trial

Dow Jones04-29

By Kelly Cloonan

Shares of Portage Biotech climbed after the company reported confirmatory data for its PORT-7 treatment of mesothelioma, supporting plans for a human trial.

The stock rose 21% to $10.23 Monday. Shares have more than doubled over the past 12 months.

The clinical stage immuno-oncology company said Monday its PORT-7, a selective adenosine A2B receptor inhibitor, demonstrated superior single agent activity compared with treatment with single agent anti-PD1 antibody in a murine model.

Combining both PORT-7 and anti-PD1 was superior to treatment with either anti-PD1 or PORT-7 alone, showing favorable immune response and increases in immune effector cells for mice in the trial, the company said.

The treatment is targeted at mesothelioma, an aggressive cancer with limited treatment options.

Portage is now making preparations to begin a first-in-human clinical trial with PORT-7, the company said.

Write to Kelly Cloonan at kelly.cloonan@wsj.com

(END) Dow Jones Newswires

April 28, 2025 13:20 ET (17:20 GMT)

Copyright (c) 2025 Dow Jones & Company, Inc.

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