Klotho Neuroscience Unveils Breakthrough in Gene Therapy Manufacturing with AAVnerGene Collaboration

Reuters08-12
Klotho Neuroscience Unveils Breakthrough in Gene Therapy Manufacturing with AAVnerGene Collaboration

Klotho Neurosciences, Inc. has announced a significant advancement in the development of its KLTO-202 gene therapy candidate. The company has initiated the manufacturing process using AAVnerGene Inc.'s innovative platform technology. This partnership leverages AAVnerGene's "AAVone" platform, which enhances the production of AAV vectors by introducing a one-plasmid system that increases efficiency, reduces impurities, and lowers development costs. The KLTO-202 candidate, which utilizes the transformative ATHENA platform for tissue-specific targeting, aims to mitigate the risks associated with traditional AAV-vectored therapies, such as liver inflammation. While these results are promising, they have not yet been presented at any scientific conference or published in a peer-reviewed journal.

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