Onco-Innovations Launches Preclinical Development of PNKP Inhibitor with Validated Analytical Methods by Nucro-Technics

Reuters2025-09-29
Onco-Innovations Launches Preclinical Development of PNKP Inhibitor with Validated Analytical Methods by Nucro-Technics

Onco-Innovations Ltd. has announced the initiation of preclinical and analytical development for its proprietary Polynucleotide Kinase Phosphatase (PNKP) inhibitor technology. In collaboration with Nucro-Technics Inc., the company has begun laboratory work to develop and validate advanced analytical methods, using liquid chromatography-mass spectrometry (LC-MS), to measure the PNKP inhibitor in preclinical samples and drug formulations. These methods are essential for regulatory submissions and will underpin future studies, including formal toxicology and pharmacokinetics assessments. The results represent a key step in Onco-Innovations' IND-enabling program and have not yet been presented, as the validated methods will serve as the foundation for upcoming research and regulatory filings.

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