Clover Biopharmaceuticals Announces Positive Phase I Data for RSV-HMPV-PIV3 Combination Vaccines, Plans Phase II Trials in 2026

Reuters10-14
Clover Biopharmaceuticals Announces Positive Phase I Data for RSV-HMPV-PIV3 Combination Vaccines, Plans Phase II Trials in 2026

Clover Biopharmaceuticals Ltd. has announced positive preliminary Phase I clinical data for its combination respiratory PreF vaccine candidates targeting RSV, hMPV, and PIV3, utilizing its Trimer-Tag platform technology. The announcement covers results from two ongoing clinical trials: one in Australia evaluating SCB-1022 (RSV+hMPV) and SCB-1033 (RSV+hMPV+PIV3) in older adults, and another in the U.S. assessing re-vaccination with SCB-1019 in individuals previously vaccinated with GSK's AREXVY. Based on these results, Clover intends to advance SCB-1022 and SCB-1033 to Phase II clinical trials in the first half of 2026. Additional data from the ongoing RSV re-vaccination trial is expected by the first half of 2026.

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