ADRs Close Lower; Quoin Pharmaceuticals Ltd. Declines 25%

Dow Jones10-23

This article was automatically generated by Dow Jones using technology from Automated Insights.

International stocks trading in New York closed lower on Wednesday, as the S&P/BNY Mellon index of American depositary receipts declined 0.2% to 227.35.

The European index gained 0.4% to 198.98. The Asian index fell 1.0% to 308.49. The Latin American index rose 0.9% to 215.15, while the emerging-markets index fell 0.9% to 513.39.

Quoin Pharmaceuticals Ltd., based in Israel, posted the largest decline, plummeting 25% to $12.10, followed by shares of Denmark's Evaxion A/S, which plunged 17% to $5.44. Shares of Japan-based Lead Real Estate Co. Ltd. tumbled 14% to $1.35.

United Kingdom's Adaptimmune Therapeutics PLC was the biggest leader during the session, soaring 49% to 7 cents, and China-based Lixiang Education Holding Co. Ltd. rocketed 24% to 45 cents. Embotelladora Andina S.A. (Series A), which is based in Chile, rounded out the top three leaders on Wednesday, with shares rising 7.9% to $19.88.

Data source: Dow Jones Market Data, FactSet

(END) Dow Jones Newswires

October 22, 2025 16:30 ET (20:30 GMT)

Copyright (c) 2025 Dow Jones & Company, Inc.

At the request of the copyright holder, you need to log in to view this content

Disclaimer: Investing carries risk. This is not financial advice. The above content should not be regarded as an offer, recommendation, or solicitation on acquiring or disposing of any financial products, any associated discussions, comments, or posts by author or other users should not be considered as such either. It is solely for general information purpose only, which does not consider your own investment objectives, financial situations or needs. TTM assumes no responsibility or warranty for the accuracy and completeness of the information, investors should do their own research and may seek professional advice before investing.

Comments

We need your insight to fill this gap

Leave a comment

{"i18n":{"language":"en_US"},"isChannel":false,"data":{"share":"https://ttm.financial/m/news/2577319056?lang=en_US&edition=fundamental","thumbnail":"","is_english":true,"pubTime":"2025-10-23 04:30","share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","id":"2577319056","market":"fut","top_or_hot":-1,"title":"ADRs Close Lower; Quoin Pharmaceuticals Ltd. Declines 25%","media":"Dow Jones","content":"<font class=\"NormalMinus1\" face=\"Arial\">\n<p>\n  This article was automatically generated by Dow Jones using technology from Automated Insights. \n</p>\n<p>\n     International stocks trading in New York closed lower on Wednesday, as the S&amp;P/BNY Mellon index of American depositary receipts declined 0.2% to 227.35. \n</p>\n<p>\n     The European index gained 0.4% to 198.98. The Asian index fell 1.0% to 308.49. The Latin American index rose 0.9% to 215.15, while the emerging-markets index fell 0.9% to 513.39. \n</p>\n<p>\n     <a href=\"https://laohu8.com/S/QNRX\">Quoin Pharmaceuticals</a> Ltd., based in Israel, posted the largest decline, plummeting 25% to $12.10, followed by shares of Denmark's Evaxion A/S, which plunged 17% to $5.44. Shares of Japan-based <a href=\"https://laohu8.com/S/LRE\">Lead Real Estate</a> Co. Ltd. tumbled 14% to $1.35. \n</p>\n<p>\n     United Kingdom's Adaptimmune <a href=\"https://laohu8.com/S/LENZ\">Therapeutics</a> PLC was the biggest leader during the session, soaring 49% to 7 cents, and China-based <a href=\"https://laohu8.com/S/LXEH\">Lixiang Education</a> Holding Co. Ltd. rocketed 24% to 45 cents. <a href=\"https://laohu8.com/S/AKO.A\">Embotelladora Andina S.A.</a> (Series A), which is based in Chile, rounded out the top three leaders on Wednesday, with shares rising 7.9% to $19.88. \n</p>\n<p>\n  Data source: Dow Jones Market Data, FactSet \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n  (END) Dow Jones Newswires\n</p>\n<p>\n  October 22, 2025 16:30 ET (20:30 GMT)\n</p>\n<p>\n  Copyright (c) 2025 Dow Jones &amp; Company, Inc.\n</p>\n</font>","source":null,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>ADRs Close Lower; Quoin Pharmaceuticals Ltd. Declines 25%</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nADRs Close Lower; Quoin Pharmaceuticals Ltd. Declines 25%\n</h2>\n\n<h4 class=\"meta\">\n\n\n<div class=\"head\" \">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/150f88aa4d182df19190059f4a365e99);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Dow Jones </p>\n<p class=\"h-time\">2025-10-23 04:30</p>\n</div>\n\n</div>\n\n\n</h4>\n\n</header>\n<article>\n<font class=\"NormalMinus1\" face=\"Arial\">\n<p>\n  This article was automatically generated by Dow Jones using technology from Automated Insights. \n</p>\n<p>\n     International stocks trading in New York closed lower on Wednesday, as the S&amp;P/BNY Mellon index of American depositary receipts declined 0.2% to 227.35. \n</p>\n<p>\n     The European index gained 0.4% to 198.98. The Asian index fell 1.0% to 308.49. The Latin American index rose 0.9% to 215.15, while the emerging-markets index fell 0.9% to 513.39. \n</p>\n<p>\n     <a href=\"https://laohu8.com/S/QNRX\">Quoin Pharmaceuticals</a> Ltd., based in Israel, posted the largest decline, plummeting 25% to $12.10, followed by shares of Denmark's Evaxion A/S, which plunged 17% to $5.44. Shares of Japan-based <a href=\"https://laohu8.com/S/LRE\">Lead Real Estate</a> Co. Ltd. tumbled 14% to $1.35. \n</p>\n<p>\n     United Kingdom's Adaptimmune <a href=\"https://laohu8.com/S/LENZ\">Therapeutics</a> PLC was the biggest leader during the session, soaring 49% to 7 cents, and China-based <a href=\"https://laohu8.com/S/LXEH\">Lixiang Education</a> Holding Co. Ltd. rocketed 24% to 45 cents. <a href=\"https://laohu8.com/S/AKO.A\">Embotelladora Andina S.A.</a> (Series A), which is based in Chile, rounded out the top three leaders on Wednesday, with shares rising 7.9% to $19.88. \n</p>\n<p>\n  Data source: Dow Jones Market Data, FactSet \n</p>\n<pre style=\"white-space: pre\">\n \n</pre>\n<p>\n  (END) Dow Jones Newswires\n</p>\n<p>\n  October 22, 2025 16:30 ET (20:30 GMT)\n</p>\n<p>\n  Copyright (c) 2025 Dow Jones &amp; Company, Inc.\n</p>\n</font>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"QNRX","symbol_name":"Quoin Pharmaceuticals","start_time":0,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","article_id":"2577319056","we_media_id":"106","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2577319056","pubTimestamp":1761165000,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Dow Jones","introduction":"Dow Jones publishes the world’s most trusted business news and financial information in a variety of media.","home_visible":0,"id":"106","head_image":"https://static.tigerbbs.com/150f88aa4d182df19190059f4a365e99"},"summary":"This article was automatically generated by Dow Jones using technology from Automated Insights.International stocks trading in New York closed lower on Wednesday, as the S&P/BNY Mellon index of American depositary receipts declined 0.2% to 227.35.The European index gained 0.4% to 198.98. The Asian index fell 1.0% to 308.49. The Latin American index rose 0.9% to 215.15, while the emerging-markets index fell 0.9% to 513.39.Quoin Pharmaceuticals Ltd., based in Israel, posted the largest decline, plummeting 25% to $12.10, followed by shares of Denmark's Evaxion A/S, which plunged 17% to $5.44. Shares of Japan-based Lead Real Estate Co. Ltd. tumbled 14% to $1.35.United Kingdom's Adaptimmune Therapeutics PLC was the biggest leader during the session, soaring 49% to 7 cents, and China-based Lixiang Education Holding Co. Ltd. rocketed 24% to 45 cents. Embotelladora Andina S.A. , which is based in Chile, rounded out the top three leaders on Wednesday, with shares rising 7.9% to $19.88.","collect":0,"end_time":0,"defaultTopTitle":"","property":[],"viewcount":null,"language":"en","relate_stocks":{"QNRX":"Quoin Pharmaceuticals","BK4139":"生物科技"},"translate_title":"ADR收盘走低；Quoin Pharmaceuticals Ltd.下跌25%","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"QNRX":1.5},"content_text":"This article was automatically generated by Dow Jones using technology from Automated Insights. \n\n\n     International stocks trading in New York closed lower on Wednesday, as the S&P/BNY Mellon index of American depositary receipts declined 0.2% to 227.35. \n\n\n     The European index gained 0.4% to 198.98. The Asian index fell 1.0% to 308.49. The Latin American index rose 0.9% to 215.15, while the emerging-markets index fell 0.9% to 513.39. \n\n\nQuoin Pharmaceuticals Ltd., based in Israel, posted the largest decline, plummeting 25% to $12.10, followed by shares of Denmark's Evaxion A/S, which plunged 17% to $5.44. Shares of Japan-based Lead Real Estate Co. Ltd. tumbled 14% to $1.35. \n\n\n     United Kingdom's Adaptimmune Therapeutics PLC was the biggest leader during the session, soaring 49% to 7 cents, and China-based Lixiang Education Holding Co. Ltd. rocketed 24% to 45 cents. Embotelladora Andina S.A. (Series A), which is based in Chile, rounded out the top three leaders on Wednesday, with shares rising 7.9% to $19.88. \n\n\n  Data source: Dow Jones Market Data, FactSet \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  October 22, 2025 16:30 ET (20:30 GMT)\n\n\n  Copyright (c) 2025 Dow Jones & Company, Inc.","kind":"highlight","is_publish_news":true,"is_publish_highlight":false,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"-2","news_tag":"","news_rank":0,"symbols":[],"gpt_button":0,"need_auth":true,"code":"91000000","status":"200"},"commentList":[],"isCommentEnd":true,"newsSizeData":{"likeSize":0,"commentSize":0,"repostSize":0,"favoriteSize":0,"likeStatus":false,"favoriteStatus":false},"APP":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)","isDev":false,"isTTM":true,"deviceId":"web-server-community-laohu8-v3","version":"4.35.12","shortVersion":"4.35.12","platform":"web","vendor":"web","appName":"ttm","isIOS":false,"isAndroid":false,"isTiger":false,"isTHS":false,"isWeiXin":false,"isWeiXinMini":false,"isWeiBo":false,"isQQ":false,"isBaiduSwan":false,"isBaiduBox":false,"isDingTalk":false,"isToutiao":false,"isOnePlus":false,"isHuaWei":false,"isXiaomi":false,"isXiaomiWebView":false,"isOppo":false,"isVivo":false,"isSamsung":false,"isMobile":false},"href":"/m/news/2577319056","isCrawlerRequest":true}