Nkarta Unveils Promising NKX019 Data for B-Cell Depletion in Autoimmune Disease Models

Reuters10-22
<a href="https://laohu8.com/S/NKTX">Nkarta</a> Unveils Promising NKX019 Data for B-Cell Depletion in Autoimmune Disease Models

Nkarta Inc., a clinical-stage biopharmaceutical company, announced that it will present new clinical data on its investigational therapy, NKX019, at the American College of Rheumatology $(ACR)$ Convergence 2025 meeting in Chicago. The data to be presented demonstrate that NKX019, an allogeneic off-the-shelf CD19 targeting CAR-NK cell therapy, achieved robust pathogenic B-cell depletion followed by reconstitution of the B cell compartment in participants with non-Hodgkin lymphoma. Preclinical studies also showed that NKX019 effectively depletes pathogenic B cells in in vivo lymphoma models and in vitro autoimmune disease models. The poster presentation is scheduled for Sunday, October 26, 2025, and the abstract is available on the ACR Convergence 2025 website.

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