ADRs End Flat; Purple Biotech Ltd. Climbs 82%

Dow Jones10-30

This article was automatically generated by Dow Jones using technology from Automated Insights.

International stocks trading in New York closed flat on Wednesday, as the S&P/BNY Mellon index of American depositary receipts held steady at 232.40.

The European index dropped 0.3% to 200.62. The Asian index added 0.2% to 319.21. The Latin American index rose 1.0% to 226.84, while the emerging-markets index increased 0.8% to 537.02.

Israel's Purple Biotech Ltd. was the biggest leader during the session, soaring 82% to $1.06, and Switzerland-based WISeKey International Holding Ltd. soared 28% to $15.92. Genenta Science S.p.A., which is based in Italy, rounded out the top three leaders on Wednesday, with shares soaring 25% to $3.01.

Quhuo Ltd., based in China, posted the largest decline, plummeting 84% to $1.26, followed by shares of France's Inventiva S.A., which cratered 21% to $4.16. Shares of Japan-based MEDIROM Healthcare Technologies Inc. plummeted 21% to $2.07.

Data source: Dow Jones Market Data, FactSet

(END) Dow Jones Newswires

October 29, 2025 16:30 ET (20:30 GMT)

Copyright (c) 2025 Dow Jones & Company, Inc.

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The Latin American index rose 1.0% to 226.84, while the emerging-markets index increased 0.8% to 537.02. \n</p>\n<p>\n     Israel's <a href=\"https://laohu8.com/S/PPBT\">Purple Biotech Ltd.</a> was the biggest leader during the session, soaring 82% to $1.06, and Switzerland-based <a href=\"https://laohu8.com/S/WSKEF\">WISeKey International Holding Ltd.</a> soared 28% to $15.92. <a href=\"https://laohu8.com/S/GNTA\">Genenta Science S.p.A.</a>, which is based in Italy, rounded out the top three leaders on Wednesday, with shares soaring 25% to $3.01. \n</p>\n<p>\n     Quhuo Ltd., based in China, posted the largest decline, plummeting 84% to $1.26, followed by shares of France's <a href=\"https://laohu8.com/S/IVA\">Inventiva S.A.</a>, which cratered 21% to $4.16. 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The Latin American index rose 1.0% to 226.84, while the emerging-markets index increased 0.8% to 537.02. \n</p>\n<p>\n     Israel's <a href=\"https://laohu8.com/S/PPBT\">Purple Biotech Ltd.</a> was the biggest leader during the session, soaring 82% to $1.06, and Switzerland-based <a href=\"https://laohu8.com/S/WSKEF\">WISeKey International Holding Ltd.</a> soared 28% to $15.92. <a href=\"https://laohu8.com/S/GNTA\">Genenta Science S.p.A.</a>, which is based in Italy, rounded out the top three leaders on Wednesday, with shares soaring 25% to $3.01. \n</p>\n<p>\n     Quhuo Ltd., based in China, posted the largest decline, plummeting 84% to $1.26, followed by shares of France's <a href=\"https://laohu8.com/S/IVA\">Inventiva S.A.</a>, which cratered 21% to $4.16. 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The Asian index added 0.2% to 319.21. The Latin American index rose 1.0% to 226.84, while the emerging-markets index increased 0.8% to 537.02.Israel's Purple Biotech Ltd. was the biggest leader during the session, soaring 82% to $1.06, and Switzerland-based WISeKey International Holding Ltd. soared 28% to $15.92. Genenta Science S.p.A., which is based in Italy, rounded out the top three leaders on Wednesday, with shares soaring 25% to $3.01.Quhuo Ltd., based in China, posted the largest decline, plummeting 84% to $1.26, followed by shares of France's Inventiva S.A., which cratered 21% to $4.16. Shares of Japan-based MEDIROM Healthcare Technologies Inc. plummeted 21% to $2.07.","collect":0,"end_time":0,"defaultTopTitle":"","property":[],"viewcount":null,"language":"en","relate_stocks":{"PPBT":"Purple Biotech Ltd.","BK4007":"制药"},"translate_title":"美国存托凭证收盘持平；Purple Biotech Ltd.上涨82%","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"PPBT":1.5},"content_text":"This article was automatically generated by Dow Jones using technology from Automated Insights. \n\n\n     International stocks trading in New York closed flat on Wednesday, as the S&P/BNY Mellon index of American depositary receipts held steady at 232.40. \n\n\n     The European index dropped 0.3% to 200.62. The Asian index added 0.2% to 319.21. The Latin American index rose 1.0% to 226.84, while the emerging-markets index increased 0.8% to 537.02. \n\n\n     Israel's Purple Biotech Ltd. was the biggest leader during the session, soaring 82% to $1.06, and Switzerland-based WISeKey International Holding Ltd. soared 28% to $15.92. Genenta Science S.p.A., which is based in Italy, rounded out the top three leaders on Wednesday, with shares soaring 25% to $3.01. \n\n\n     Quhuo Ltd., based in China, posted the largest decline, plummeting 84% to $1.26, followed by shares of France's Inventiva S.A., which cratered 21% to $4.16. 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