Karyopharm Therapeutics Reports Third Quarter Net Loss of $33.1 Million on Revenue of $44 Million

Reuters11-03

Karyopharm <a href="https://laohu8.com/S/LENZ">Therapeutics</a> Reports Third Quarter Net Loss of $33.1 Million on Revenue of $44 Million

Karyopharm Therapeutics Inc. reported a net loss of $33.1 million, or $3.82 per basic and diluted share, for the third quarter of 2025, compared to a net loss of $32.1 million, or $3.85 per basic and diluted share, for the same period in 2024. Total revenue for the third quarter of 2025 was $44.0 million. U.S. XPOVIO net product revenue reached $32.0 million, an increase of 8.5% from $29.5 million in the third quarter of 2024. The company reaffirmed its full-year 2025 total revenue guidance of $140 million to $155 million and U.S. XPOVIO net product revenue guidance of $110 million to $120 million. Karyopharm completed enrollment in its Phase 3 SENTRY trial in myelofibrosis, with top-line data expected in March 2026.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Karyopharm Therapeutics Inc. published the original content used to generate this news brief via PR Newswire (Ref. ID: NE13128) on November 03, 2025, and is solely responsible for the information contained therein.

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