United Therapeutics Begins First Clinical Trial of Gene-Edited Pig Kidney Transplant for ESRD

Reuters11-03

United <a href="https://laohu8.com/S/LENZ">Therapeutics</a> Begins First Clinical Trial of Gene-Edited Pig Kidney Transplant for ESRD

United Therapeutics Corporation has announced the first clinical xenotransplantation in its EXPAND study, involving the UKidney™ for patients with end-stage renal disease (ESRD). The procedure was performed at NYU Langone Health. The UKidney is an investigational xenokidney derived from a pig with 10 gene edits-six human genes were added to improve immunological acceptance, and four porcine genes were inactivated to reduce organ rejection and moderate growth. The EXPAND study aims to provide an alternative to human donor kidneys, especially for patients unlikely to receive a transplant from a human donor. Results from the study have not yet been presented, as the trial is ongoing.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. United Therapeutics Corporation published the original content used to generate this news brief via Business Wire (Ref. ID: 20251103435431) on November 03, 2025, and is solely responsible for the information contained therein.

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