Compass Pathways plc has shared updates on its ongoing clinical programs targeting treatment-resistant depression (TRD) and post-traumatic stress disorder (PTSD). The company highlighted a large unmet need in the TRD market, with approximately 3 million patients in the U.S. alone. Data from the Phase 3 COMP005 trial showed that COMP360 psilocybin achieved the primary endpoint, with a clinically meaningful mean treatment difference of -3.6 points on the MADRS depression scale compared to placebo (p<0.001). Safety data reviewed by the Data Safety Monitoring Board indicated no new or unexpected findings and no evidence of a clinically meaningful imbalance in suicidality between treatment arms. Additional efficacy data demonstrated a rapid and durable response following a single dose of COMP360. Upcoming data releases from ongoing trials are expected in 2026. You can access the full presentation through the link below.
Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Compass Pathways plc published the original content used to generate this news brief on November 04, 2025, and is solely responsible for the information contained therein.
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