Calidi Biotherapeutics Unveils Promising CLD-401 Data at SITC Annual Meeting

Reuters11-10

<a href="https://laohu8.com/S/CLDI">Calidi Biotherapeutics</a> Unveils Promising CLD-401 Data at SITC Annual Meeting

Calidi Biotherapeutics Inc. announced new data on its lead therapeutic candidate, CLD-401, at the 2025 Society of Immunotherapy for Cancer $(SITC)$ Annual Meeting. CLD-401, developed using Calidi's RedTail platform, is a tumor-tropic oncolytic virus designed for systemic administration that selectively replicates in tumor cells, induces immune priming at the tumor site, and expresses high levels of IL-15 superagonist in the tumor microenvironment. According to the company, preclinical syngeneic models demonstrated targeted delivery and expression of IL-15 superagonist in tumors with minimal systemic exposure. The latest results were presented at SITC 2025. Calidi is currently conducting IND-enabling studies for CLD-401 and anticipates submitting an Investigational New Drug (IND) application by the end of 2026.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Calidi Biotherapeutics Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9571996-en) on November 10, 2025, and is solely responsible for the information contained therein.

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CLD-401, developed using Calidi's RedTail platform, is a tumor-tropic oncolytic virus designed for systemic administration that selectively replicates in tumor cells, induces immune priming at the tumor site, and expresses high levels of IL-15 superagonist in the tumor microenvironment. According to the company, preclinical syngeneic models demonstrated targeted delivery and expression of IL-15 superagonist in tumors with minimal systemic exposure. The latest results were presented at SITC 2025. Calidi is currently conducting IND-enabling studies for CLD-401 and anticipates submitting an Investigational New Drug (IND) application by the end of 2026.\n      </p>\n</div><div xmlns:xsd=\"http://www.w3.org/2001/XMLSchema\" xmlns:xsi=\"http://www.w3.org/2001/XMLSchema-instance\">\n<em>Disclaimer: <span>This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. 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