Passage Bio Unveils Gene Therapy Advances Targeting Neurodegenerative Diseases

Reuters11-11

<a href="https://laohu8.com/S/PASG">Passage Bio</a> Unveils Gene Therapy Advances Targeting Neurodegenerative Diseases

Passage Bio Inc. presented updates on its gene therapy program PBFT02, which targets frontotemporal dementia with progranulin gene mutations (FTD-GRN). The therapy is designed as a one-time, proprietary AAV1 gene replacement administered via nonsurgical injection to the cerebrospinal fluid, aiming to restore progranulin levels and address the underlying cause of FTD-GRN. Interim clinical data indicate durable elevation of progranulin in treated patients. The company highlighted the significant market opportunity for PBFT02 across several neurodegenerative diseases, including ALS and Alzheimer's disease associated with GRN mutations. Passage Bio also reported that its current cash position is expected to support operations into the first quarter of 2027. You can access the full presentation through the link below.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Passage Bio Inc. published the original content used to generate this news brief on November 10, 2025, and is solely responsible for the information contained therein.

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