Zentalis Pharmaceuticals reports $280.7 million in cash and maintains guidance for DENALI trial topline data by year end 2026

Reuters11-11
Zentalis Pharmaceuticals reports $280.7 million in cash and maintains guidance for DENALI trial topline data by year end 2026

Zentalis Pharmaceuticals reported cash, cash equivalents, and marketable securities of $280.7 million as of September 30, 2025, which the company expects to fund operations into late 2027. Research and development expenses for the third quarter of 2025 were $23.0 million, down from $36.8 million in the same period in 2024, primarily due to reduced personnel, lab services, clinical expenses, and other costs. General and administrative expenses were $10.8 million, compared to $14.6 million in the third quarter of 2024, mainly due to lower personnel expenses. The company highlighted continued progress in its Phase 2 DENALI clinical trial of azenosertib in Cyclin E1-positive platinum-resistant ovarian cancer, with topline data expected by year end 2026 and results from the TETON trial planned for publication in the first half of 2026.

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