Sagimet Biosciences Inc. reported cash, cash equivalents, and marketable securities of $125.5 million as of September 30, 2025. Research and development expenses for the third quarter of 2025 were $9.7 million, compared to $12.7 million for the same period in 2024. For the nine months ended September 30, 2025, research and development expenses totaled $32.3 million, up from $24.2 million in the prior year period. During the period, Sagimet initiated a Phase 1 clinical trial of FASN inhibitor TVB-3567 for acne and continued a Phase 1 trial evaluating the combination of denifanstat and resmetirom, with data readouts expected in the first half of 2026. Ascletis, the company's license partner in China, completed a pre-NDA consultation and plans to submit an NDA for denifanstat for moderate-to-severe acne vulgaris.
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