Sagimet Biosciences Launches Phase 1 Trial of Denifanstat and Resmetirom Combination for MASH

Reuters11-13

Sagimet Biosciences Launches Phase 1 Trial of Denifanstat and Resmetirom Combination for MASH

Sagimet Biosciences Inc. has announced the ongoing Phase 1 clinical trial evaluating the pharmacokinetics $(PK)$ and tolerability of a combination of denifanstat and resmetirom, with data readout expected in the first half of 2026. Additionally, Sagimet has initiated a first-in-human Phase 1 clinical trial of its second FASN inhibitor, TVB-3567, aimed at developing an acne indication. The company anticipates starting a Phase 2 clinical trial in moderate to severe acne patients in 2026, subject to regulatory consultation, following completion of the ongoing Phase 1 study of TVB-3567. No results from these studies have been presented yet.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Sagimet Biosciences Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9574799-en) on November 13, 2025, and is solely responsible for the information contained therein.

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Additionally, Sagimet has initiated a first-in-human Phase 1 clinical trial of its second FASN inhibitor, TVB-3567, aimed at developing an acne indication. The company anticipates starting a Phase 2 clinical trial in moderate to severe acne patients in 2026, subject to regulatory consultation, following completion of the ongoing Phase 1 study of TVB-3567. No results from these studies have been presented yet.\n      \n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Sagimet Biosciences Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. 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