MiNK Therapeutics Reports MiNK-215 Shows Strong Anti-Tumor Activity in Resistant Solid Tumors

Reuters11-21

MiNK <a href="https://laohu8.com/S/LENZ">Therapeutics</a> Reports MiNK-215 Shows Strong Anti-Tumor Activity in Resistant Solid Tumors

MiNK Therapeutics Inc. has announced new preclinical research results for its novel therapy, MiNK-215, which targets solid tumors resistant to current immunotherapies. The findings, now published in Cancer Immunology Research, show that MiNK-215-an IL-15-enhanced, FAP-targeting CAR-iNKT cell therapy-can effectively dismantle tumor-protective fibroblast barriers, remodel the tumor microenvironment, and activate multiple immune pathways. In models of lung and microsatellite stable $(MSS)$ colorectal cancer, MiNK-215 promoted immune cell infiltration, activated dendritic cells, re-polarized macrophages, and enabled robust anti-tumor activity. As an off-the-shelf, allogeneic therapy, MiNK-215 offers a scalable treatment option for patients with solid tumors that have not responded to conventional immune-based therapies.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Mink Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9579795-en) on November 20, 2025, and is solely responsible for the information contained therein.

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