Skye Bioscience Unveils Presentation Highlighting Nimacimab’s Potential to Enhance Obesity Treatments

Reuters11-24
Skye Bioscience Unveils Presentation Highlighting Nimacimab's Potential to Enhance Obesity Treatments

Skye Bioscience Inc. has provided an update on the development of nimacimab, a novel therapeutic candidate for obesity and metabolic diseases. According to the presentation, nimacimab is positioned as a complementary treatment to existing GLP-1 therapies, offering approximately 3% additional weight loss when used in combination with semaglutide over 26 weeks. The data also indicate a lower rate of post-treatment weight rebound and a favorable body composition profile compared to GLP-1 monotherapy. The company highlights nimacimab's differentiated peripheral CB1 mechanism, which does not increase gastrointestinal or neuropsychiatric adverse events in combination regimens. Skye Bioscience reports a clear pharmacokinetic and exposure-response profile from Phase 2a studies and is planning further evaluation at higher doses. Nimacimab is presented as suitable for both patients who do not respond to or tolerate GLP-1 therapies and for those seeking enhanced weight loss outcomes. You can access the full presentation through the link below.

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