Sarepta Therapeutics Advances SRP-1003 Myotonic Dystrophy Trial to Higher Dose Cohorts

Reuters11-24

<a href="https://laohu8.com/S/SRPT">Sarepta Therapeutics</a> Advances SRP-1003 Myotonic Dystrophy Trial to Higher Dose Cohorts

Sarepta Therapeutics Inc. has provided an update on its Phase 1/2 multiple ascending dose clinical study of SRP-1003, an investigational small interfering RNA (siRNA) therapeutic for the treatment of type 1 myotonic dystrophy (DM1). Cohorts 1 (1.5 mg/kg) and 2 (3 mg/kg) have been completed, while cohort 3 (4.5 mg/kg) is fully enrolled and ongoing. Following a positive pre-specified drug safety committee review, the study is advancing with additional dose escalation cohorts. Patients are currently being dosed in cohort 4 (6 mg/kg), with plans to initiate dosing in the final cohort (12 mg/kg) in early 2026. Study results have not yet been presented.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Sarepta Therapeutics Inc. published the original content used to generate this news brief via Business Wire (Ref. ID: 20251124527957) on November 24, 2025, and is solely responsible for the information contained therein.

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